Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91153 | 0.97 | — | — | |
| SCHEMBL29629596 | 0.97 | — | — | |
| SCHEMBL28686760 | 0.95 | ALOX15 (0.54) | ALOX15HSD17B10TSHRALDH1A1HPGD | |
| SCHEMBL28708943 | 0.95 | ALOX15 (0.54) | ALOX15HSD17B10TSHRALDH1A1HPGD | |
| SCHEMBL28936596 | 0.83 | HSD17B10 (0.48) | ALOX15HSD17B10TSHRALDH1A1HPGD | |
| SCHEMBL15674635 | 0.79 | ALOX5 (0.65) | ALOX15HSD17B10TSHRALDH1A1HPGD | |
| SCHEMBL897593 | 0.77 | — | — | |
| SCHEMBL25876566 | 0.74 | THRA (0.50) | ALOX15HSD17B10TSHRHSP90AA1ALOX5 | |
| SCHEMBL8633861 | 0.74 | MAOA (0.44) | ALOX15HSD17B10TSHRALDH1A1HPGD | |
| 2,4-Dichlorophenol SCHEMBL27937117 | 0.74 | HSD17B10 (0.94) | ALOX15HSD17B10TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072386-A | Improved process for the preparation of key intermediates for the synthesis of eltrombopag or salts thereof | F.I.S.-菲博利佳意大利合成面料股份公司 | 2022-02-18 | — | — | CN | disclosed |