Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ARF6 | P62330 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 3/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189622 | 0.87 | IDO1 (0.39) | IDO1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL9336031 | 0.86 | MAPK14 (0.39) | IDO1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL9446465 | 0.85 | ALDH1A1 (0.45) | IDO1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL1180132 | 0.84 | ALDH1A1 (0.48) | IDO1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL9446464 | 0.82 | ALDH1A1 (0.45) | IDO1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL7500352 | 0.80 | IDO1 (0.44) | IDO1KMT2AHPGDMEN1HTT | |
| SCHEMBL9446515 | 0.80 | MAPK14 (0.44) | IDO1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL9273773 | 0.78 | ALDH1A1 (0.35) | KMT2AALDH1A1GAAHPGDKDM4E | |
| SCHEMBL9226704 | 0.78 | MAPK14 (0.43) | IDO1KMT2AHPGDMEN1LMNA | |
| SCHEMBL9336072 | 0.76 | IDO1 (0.43) | IDO1KMT2AHPGDMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563279-A | Debrominative chlorination of pyrroles | AMERICAN CYANAMID COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| US-5449789-A | Debrominative chlorination of pyrroles | AMERICAN CYANAMID COMPANY (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0600157-A1 | Debrominative chlorination of pyrroles | AMERICAN CYANAMID COMPANY (US) | 1994-06-08 | — | — | EP | disclosed |