Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224576 | 0.89 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAGAAHTT | |
| SCHEMBL9015062 | 0.88 | KDM4E (0.48) | ALDH1A1KDM4ELMNAGAAHTT | |
| SCHEMBL9567335 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAGAAHTT | |
| SCHEMBL9189605 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAGAAHTT | |
| SCHEMBL13858869 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAGAAHTT | |
| SCHEMBL116957 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAGAAHTT | |
| SCHEMBL8976164 | 0.84 | IDO1 (0.40) | ALDH1A1KDM4ELMNAGAAHTT | |
| SCHEMBL9446485 | 0.82 | GRM5 (0.47) | ALDH1A1KDM4ELMNAGAAHTT | |
| SCHEMBL27934886 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAGAAHTT | |
| SCHEMBL9273773 | 0.81 | ALDH1A1 (0.35) | ALDH1A1KDM4ELMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895839-B1 | Arylpyrroles for the protection of wood, wood products and wood structures from insect attack | BASF AG (DE) | 2006-09-20 | — | — | EP | claimed |
| EP-0746979-B1 | Use of pyrrole compounds as antifouling agents | BASF AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-0895717-B1 | Arylpyrroles for subterranean termite control | BASF AG (DE) | 2003-05-28 | — | — | EP | claimed |
| US-5932520-A | FOR MARINE SURFACES | AMERICAN CYANAMID COMPANY (US) | 1999-08-03 | — | — | US | claimed |
| EP-0895717-A1 | Arylpyrroles for subterranean termite control | American Cyanamid Company (US) | 1999-02-10 | — | — | EP | claimed |
| EP-0895839-A1 | Arylpyrroles for the protection of wood, wood products and wood structures from insect attack | American Cyanamid Company (US) | 1999-02-10 | — | — | EP | claimed |
| EP-0746979-A1 | Use of pyrrole compounds as antifouling agents | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | claimed |
| EP-3231283-A1 | BIOCIDE COMPOSITION COMPRISING ZINC PYRITHIONE AND A PYRROLE DERIVATIVE | Arch Chemicals, Inc. (US) | 2017-10-18 | — | — | EP | disclosed |
| US-8481523-B2 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-8372829-B2 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. (US) | 2013-02-12 | — | — | US | disclosed |
| US-20110144232-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. | 2011-06-16 | — | — | US | disclosed |
| US-20110143153-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. | 2011-06-16 | — | — | US | disclosed |
| US-20110104375-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. | 2011-05-05 | — | — | US | disclosed |
| EP-0491136-B1 | Process for the manufacture of pesticidal 1-(alkoxymethyl)pyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-09-18 | — | — | EP | disclosed |
| US-5449789-A | Debrominative chlorination of pyrroles | AMERICAN CYANAMID COMPANY (US) | 1995-09-12 | — | — | US | disclosed |
| US-5187184-A | Mixtures of substituted arylpyrroles and arylpyrazoles | AMERICAN CYANAMID COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| US-5151536-A | Insecticides, molluscicides, miticides or nematocides | AMERICAN CYANAMID COMPANY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5128485-A | SYNTHESIS OF 2-ARYL-5-(TRIFLUOROMETHYL)PYRROLES USEFUL AS PESTICIDAL AGENTS AND AS INTERMEDIATES FOR THE PREPARATION OF SAID AGENTS | AMERICAN CYANAMID COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0492125-A1 | Insecticidal and synergistic miticidal compositions | AMERICAN CYANAMID COMPANY (US) | 1992-07-01 | — | — | EP | disclosed |
| EP-0491136-A2 | Process for the manufacture of pesticidal 1-(alkoxymethyl)pyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144232-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | PYCR1, CAT, BBOX1 | ALDH1A1 149/4885KDM4E 3108/4885LMNA 4774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.