Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125355 | 0.87 | ESR1 (0.65) | ESR1ESR2MEN1KMT2AALDH1A1 | |
| SCHEMBL28391516 | 0.85 | ESR2 (0.53) | ESR1ESR2KMT2ALTA4HALDH1A1 | |
| SCHEMBL4453589 | 0.80 | LTA4H (0.48) | LTA4HNR1H2BAXALDH1A1SMN1; SMN2 | |
| SCHEMBL27579613 | 0.79 | ESR1 (0.56) | ESR1ESR2MEN1KMT2AALDH1A1 | |
| Water SCHEMBL8862151 | 0.78 | MEN1 (0.93) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL1979669 | 0.76 | ESR1 (0.70) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL17106643 | 0.76 | ESR1 (0.70) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL3175106 | 0.75 | ESR2 (1.00) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL18198 | 0.75 | ESR2 (1.00) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL7811939 | 0.75 | ESR2 (1.00) | ESR1ESR2MEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180036970-A1 | PULTRUDED ARTICLES AND METHODS FOR MAKING SAME | ZEPHYROS, INC. | 2018-02-08 | — | — | US | disclosed |
| EP-0589939-B1 | HYDROXY-FUNCTIONAL POLY(ETHER SULFONAMIDES) AS THERMOPLASTIC BARRIER RESINS | DOW CHEMICAL CO (US) | 1996-03-27 | — | — | EP | disclosed |