SCHEMBL8976258

SCHEMBL8976258

Cc1ccc(C(C2=CC=CC2)C2=CC=CC2)cc1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.35
GAA P10253 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ACHE P22303 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
MGAM O43451 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20913264 0.96 CHRNA7 (0.35) CHRNA7GAAMEN1KMT2AACHE
SCHEMBL7719567 0.81 SLC6A3 (0.37) GAAMEN1KMT2ALMNAMAPT
Hydrochloric Acid SCHEMBL8677325 0.78 SLC6A2 (0.39) GAAMEN1KMT2ALMNAMAPT
Hydrochloric Acid SCHEMBL8677321 0.78 SLC6A2 (0.34) GAAMEN1KMT2ATDP1LMNA
SCHEMBL28838088 0.77 SLC6A3 (0.37) GAAMEN1KMT2ALMNAMAPT
SCHEMBL21044901 0.76 GAA (0.37) GAAMEN1KMT2AMAPT
SCHEMBL16458585 0.75
SCHEMBL12815263 0.73 MAPT (0.38) GAAACHEMAPTMGAMSI
SCHEMBL122911 0.71 ACHE (0.57) CHRNA7GAAMEN1KMT2AACHE
SCHEMBL15915166 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514338-B1 Mixtures of sprioheptadiene compounds CIBA GEIGY AG (CH) 1996-03-27 EP disclosed
US-5262501-A Oligomers for laminates for copper printed circuits CIGA-GEIGY CORPORATION (US) 1993-11-16 US disclosed
EP-0514338-A1 Mixtures of sprioheptadiene compounds CIBA-GEIGY AG (CH) 1992-11-19 EP disclosed