Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598597 | 0.69 | SIGMAR1 (0.38) | ALDH1A1HSD11B1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11164189 | 0.65 | HSD11B1 (0.39) | MEN1ALDH1A1KMT2AHSD11B1GRIN2D | |
| Hydrochloric Acid SCHEMBL7107185 | 0.65 | ALDH1A1 (0.35) | MEN1ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL12439809 | 0.64 | SIGMAR1 (0.38) | MEN1ALDH1A1KMT2AHSD11B1GRIN2D | |
| SCHEMBL821936 | 0.64 | GRIN2D (0.46) | MEN1ALDH1A1KMT2AGRIN2DGRIN3B | |
| SCHEMBL2915914 | 0.63 | GRIN2D (0.42) | MEN1ALDH1A1KMT2AGRIN2DGRIN3B | |
| SCHEMBL31254406 | 0.63 | SIGMAR1 (0.42) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL985712 | 0.62 | ABL1 (0.39) | MEN1ALDH1A1KMT2AGRIN2DGRIN3B | |
| SCHEMBL985709 | 0.62 | ABL1 (0.39) | MEN1ALDH1A1KMT2AGRIN2DGRIN3B | |
| SCHEMBL985710 | 0.62 | ABL1 (0.39) | MEN1ALDH1A1KMT2AGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561863-B1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY | ROTTA RESEARCH LAB (IT) | 1994-11-02 | — | — | EP | claimed |
| EP-0561863-A1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY. | ROTTA RESEARCH LAB (IT) | 1993-09-29 | — | — | EP | claimed |
| WO-1992010479-A1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1992-06-25 | — | — | WO | claimed |
| JP-1279893-A | — | — | None | — | — | JP | disclosed |
| US-5500430-A | Amidic derivatives of glutamic, aspartic and 2-amino adipic acids, a process for preparing same, and anti-gastrin composition containing the derivatives | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1996-03-19 | — | — | US | disclosed |
| EP-0561863-B1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY | ROTTA RESEARCH LAB (IT) | 1994-11-02 | — | — | EP | disclosed |
| EP-0561863-B1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY | ROTTA RESEARCH LAB (IT) | 1994-11-02 | — | — | EP | disclosed |
| EP-0561863-A1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY. | ROTTA RESEARCH LAB (IT) | 1993-09-29 | — | — | EP | disclosed |
| EP-0561863-A1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY. | ROTTA RESEARCH LAB (IT) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010479-A1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992010479-A1 | AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1992-06-25 | — | — | WO | disclosed |
| JP-H01279893-A | CEPHEM COMPOUND | FUJISAWA PHARMACEUT CO LTD | 1989-11-10 | — | — | JP | disclosed |