SCHEMBL8976394

SCHEMBL8976394

CCC(C)(C)c1cccc(C(C)(C)C)c1[O]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.43
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
ALDH1A1 P00352 2/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
MAPK1 P28482 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 1/20 0.34
CASP3 P42574 1/20 0.34
ATM Q13315 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
NLRP3 Q96P20 1/20 0.33
NPSR1 Q6W5P4 2/20 0.33
KIF11 P52732 1/20 0.32
ALOX12 P18054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29260335 0.93 NPC1 (0.37) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL438553 0.86 CA2 (0.55) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL2916950 0.77 CA2 (0.71) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL6386087 0.77 CA2 (0.39) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL779788 0.76 MAPK1 (0.41) CA2ALDH1A1TSHRTDP1NPC1
SCHEMBL1535124 0.76 MAPK1 (0.39) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL5896095 0.75 NPC1 (0.33) CA2GABRA1GABRB2TSHRNPC1
SCHEMBL780023 0.75 CA2 (0.37) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL29233351 0.75 CA2 (0.37) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL26027385 0.74 ALDH1A1 (0.38) CA2GABRA1GABRB2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0593653-B1 POLYMERIZATION PROCESS AND PRODUCTS SHELL OIL CO (US) 1996-09-25 EP disclosed
EP-0588800-B1 POLYMERIZATION PROCESS AND PRODUCTS SHELL OIL CO (US) 1996-04-17 EP disclosed
EP-0593653-A1 POLYMERIZATION PROCESS AND PRODUCTS. SHELL OIL CO (US) 1994-04-27 EP disclosed
EP-0588800-A1 POLYMERIZATION PROCESS AND PRODUCTS. SHELL OIL CO (US) 1994-03-30 EP disclosed
WO-1993001223-A1 POLYMERIZATION PROCESS AND PRODUCTS SHELL OIL COMPANY (US) 1993-01-21 WO disclosed
WO-1992022597-A1 POLYMERIZATION PROCESS AND PRODUCTS SHELL OIL COMPANY (US) 1992-12-23 WO disclosed
US-5143992-A Methathesis polymerizable adducts of a divinylcyclohydrocarbon and cyclopentadiene SHELL OIL COMPANY (US) 1992-09-01 US disclosed
US-5095082-A Polymerization process employing mixture of Diels-Alder adducts of 4-vinylcyclohexene and cyclopentadiene SHELL OIL COMPANY (US) 1992-03-10 US disclosed