Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976394 | 0.86 | CA2 (0.43) | CA2GABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL396284 | 0.85 | GABRA1 (0.56) | CA2GABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL1274717 | 0.79 | GABRA1 (0.41) | CA2GABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL11239902 | 0.78 | CA2 (0.40) | CA2GABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL2261916 | 0.78 | CA2 (0.40) | CA2GABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL1274720 | 0.78 | CA2 (0.40) | CA2GABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL22686107 | 0.78 | CA2 (0.44) | CA2GABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL1274942 | 0.76 | CA2 (0.39) | CA2GABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL1535127 | 0.76 | CA2 (0.48) | CA2GABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL29260335 | 0.76 | NPC1 (0.37) | CA2GABRA1GABRB2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 999 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3662996-A2 | MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS | Verbio Vereinigte BioEnergie AG (DE) | 2020-06-10 | — | — | EP | claimed |
| US-10343153-B2 | Metathesis catalysts and reactions using the catalysts | XIMO AG (CH) | 2019-07-09 | — | — | US | claimed |
| CN-109415459-A | Copolymer and preparation method thereof based on alkene | LG化学株式会社 | 2019-03-01 | — | — | CN | claimed |
| US-9924721-B2 | Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-27 | — | — | US | claimed |
| CN-104974321-B | A kind of methyl-etherified melamine resin and preparation method thereof | 江苏国立化工科技有限公司 | 2017-07-07 | — | — | CN | claimed |
| US-9499455-B2 | Process for the selective dimerisation of ethylene to 1-butene | IFP Energies Nouvelles (FR) | 2016-11-22 | — | — | US | claimed |
| US-20160198713-A1 | Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-14 | — | — | US | claimed |
| EP-3039023-A1 | MALONIC ESTER DERIVATIVES OF HETEROARYLPIPERIDINES AND -PIPERAZINES AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-07-06 | — | — | EP | claimed |
| CN-105705503-A | Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides | 拜耳作物科学股份公司 | 2016-06-22 | — | — | CN | claimed |
| US-20160030936-A1 | METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS | VERBIO SE (DE) | 2016-02-04 | — | — | US | claimed |
| WO-2003024939-A2 | TRIAZINE COMPOUNDS POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND PROCESSES FOR THE PREPARATION OF THESE POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2003-03-27 | — | — | WO | claimed |
| EP-1105397-B1 | THREE COORDINATE ALUMINUM CATALYST ACTIVATOR COMPOSITION | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-03-05 | — | — | EP | claimed |
| US-6528449-B1 | Polymerization catalysts such as /tertbutylamido/tetramethyl-cyclopentadienyl/ dimethylsilanetitanium 1,3-pentadiene and isobutyl(perfluorophenyl)-4,6-di-(t-butyl) phenoxyaluminum | THE DOW CHEMICAL COMAPNY | 2003-03-04 | — | — | US | claimed |
| CN-1098864-C | Polymerization catalyst containing active free radical of Lewis acid and its use | UNIV HUADONG SCI & ENG (CN) | 2003-01-15 | — | — | CN | claimed |
| US-20020034829-A1 | Combinatorial synthesis and analysis of metal-ligand compositions using soluble metal precursors | SYMYX TECHNOLOGIES, INC. | 2002-03-21 | — | — | US | claimed |
| CN-1314919-A | method for hydrogenating conjugated diene polymer | KOREA KUMHO PHTROCHEMICAL CO L (KR) | 2001-09-26 | — | — | CN | claimed |
| EP-1105397-A1 | THREE COORDINATE ALUMINUM CATALYST ACTIVATOR COMPOSITION | THE DOW CHEMICAL COMPANY (US) | 2001-06-13 | — | — | EP | claimed |
| US-6187940-B1 | A FLUORINATED AROMATIC HYDROCARBYL ALUMINUM COMPOUND USE AS ACTIVATORS FOR ACTIVATION OF METAL COMPLEXES IN OLEFIN POLYMERIZATIONS; IMPROVED EFFICIENCY AND OPERABILITY | THE DOW CHEMICAL COMPANY | 2001-02-13 | — | — | US | claimed |
| WO-2000009513-A1 | THREE COORDINATE ALUMINUM CATALYST ACTIVATOR COMPOSITION | THE DOW CHEMICAL COMPANY (US) | 2000-02-24 | — | — | WO | claimed |
| CN-1210868-A | Polymerization catalyst containing active free radical of Lewis acid and its use | UNIV HUADONG SCI & ENG (CN) | 1999-03-17 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10343153-B2 | Metathesis catalysts and reactions using the catalysts | MSMO1, SQLE, MOGAT2 | CA2 3454/4885GABRA1 4062/4885GABRB2 4126/4885 |
| US-20160198713-A1 | Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides | ME1, CYP1A1, CYP1A2 | CA2 378/4885GABRA1 1133/4885GABRB2 2077/4885 |
| US-20160030936-A1 | METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS | MSMO1, SQLE, PYM1 | CA2 3970/4885GABRA1 4622/4885GABRB2 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.