Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976410 | 1.00 | MEN1 (0.58) | MEN1KMT2AFAAHSMN1; SMN2KDM4E | |
| SCHEMBL8954085 | 0.81 | KMT2A (0.69) | MEN1KMT2AFAAHSMN1; SMN2KDM4E | |
| SCHEMBL8954080 | 0.81 | KMT2A (0.69) | MEN1KMT2AFAAHSMN1; SMN2KDM4E | |
| SCHEMBL16673587 | 0.80 | FAAH (0.71) | MEN1KMT2AFAAHSMN1; SMN2KDM4E | |
| SCHEMBL8976961 | 0.79 | ALDH1A1 (0.55) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8976956 | 0.79 | ALDH1A1 (0.55) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL16598924 | 0.79 | APP (0.65) | MEN1KMT2AFAAHSMN1; SMN2ALDH1A1 | |
| SCHEMBL16598922 | 0.79 | APP (0.65) | MEN1KMT2AFAAHSMN1; SMN2ALDH1A1 | |
| SCHEMBL8976627 | 0.77 | MEN1 (0.67) | MEN1KMT2AFAAHSMN1; SMN2KDM4E | |
| SCHEMBL8976630 | 0.77 | MEN1 (0.67) | MEN1KMT2AFAAHSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707004-A1 | 1-Arylalcenyl 4-arylmethylpiperazinderivatives, process for their preparation and pharmaceutical composition containing them | ADIR ET COMPAGNIE (FR) | 1996-04-17 | — | — | EP | disclosed |