Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.45 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976956 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EALOX15HSD17B10 | |
| SCHEMBL8954085 | 0.81 | KMT2A (0.69) | ALDH1A1LMNAKDM4EHSD17B10MAPK1 | |
| SCHEMBL8954080 | 0.81 | KMT2A (0.69) | ALDH1A1LMNAKDM4EHSD17B10MAPK1 | |
| SCHEMBL8976751 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EALOX15HSD17B10 | |
| SCHEMBL8976746 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EALOX15HSD17B10 | |
| SCHEMBL8976410 | 0.79 | MEN1 (0.58) | ALDH1A1LMNAKDM4EMAPK1KMT2A | |
| SCHEMBL8976405 | 0.79 | MEN1 (0.58) | ALDH1A1LMNAKDM4EMAPK1KMT2A | |
| SCHEMBL10825084 | 0.75 | ALDH1A1 (0.70) | ALDH1A1LMNAKDM4EMAPK1KMT2A | |
| SCHEMBL8976627 | 0.75 | MEN1 (0.67) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL8976630 | 0.75 | MEN1 (0.67) | ALDH1A1LMNAKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707004-A1 | 1-Arylalcenyl 4-arylmethylpiperazinderivatives, process for their preparation and pharmaceutical composition containing them | ADIR ET COMPAGNIE (FR) | 1996-04-17 | — | — | EP | disclosed |