SCHEMBL8976463

SCHEMBL8976463

C=CCOC(=O)c1c(OC)cc2c(OC)c3c(OC)ccc(OC)c3c(OC)c2c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.40
LMNA P02545 3/20 0.40
HPGD P15428 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
ALDH1A1 P00352 5/20 0.39
TSHR P16473 2/20 0.39
MAPK1 P28482 2/20 0.39
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38
GABRA4 P48169 1/20 0.38
GABRE P78334 1/20 0.38
GABRA6 Q16445 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8952310 0.87 MAPT (0.47) LMNASMN1; SMN2ALDH1A1GABRA1GABRA5
SCHEMBL8976115 0.82 CYP3A4 (0.43) KDM4EHPGDALDH1A1MAPK1CYP3A4
SCHEMBL8976444 0.81 PRKCZ (0.45) SMN1; SMN2TSHRMAPK1HSD17B10KMT2A
SCHEMBL9316220 0.80 KDM4E (0.36) KDM4ELMNAHPGDSMN1; SMN2ALDH1A1
SCHEMBL8952390 0.79 CYP3A4 (0.46) KDM4ELMNAHPGDSMN1; SMN2ALDH1A1
SCHEMBL8976409 0.79 KDM4E (0.42) KDM4ELMNAHPGDALDH1A1CYP3A4
SCHEMBL8952362 0.75 LMNA (0.47) KDM4ELMNAHPGDSMN1; SMN2ALDH1A1
SCHEMBL8952412 0.71 MAPT (0.41) KDM4EHPGDCYP3A4MAPTKMT2A
SCHEMBL17509445 0.70 CYP3A4 (0.49) KDM4ELMNAHPGDSMN1; SMN2ALDH1A1
SCHEMBL8952344 0.70 MAPT (0.44) KDM4ECYP3A4GAAMAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602027-B1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROP COLOUR PLC (GB) 1996-03-27 EP claimed
EP-0602027-B1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROP COLOUR PLC (GB) 1996-03-27 EP disclosed
US-5492690-A ABSORB ULTRAVIOLET LIGHT, CHELATE METALS TO INHIBIT FORMATION OF FREE RADICALS THE PROCTER & GAMBLE COMPANY (US) 1996-02-20 US disclosed
US-5487884-A CYTOPROTECTIVE AGENTS BY RADIATION RESISTANCE TO PREVENT SKIN CANCER AND PREMATURE AGING THE PROCTER & GAMBLE COMPANY (US) 1996-01-30 US disclosed
US-5462963-A Chelator compositions comprising α-diamine compounds THE PROCTER & GAMBLE COMPANY (US) 1995-10-31 US disclosed
US-5456904-A Sunscreens; sunblocks; antiinflammatories THE PROCTER & GAMBLE COMPANY (US) 1995-10-10 US disclosed
US-5439954-A Cosmetics for topical application to skin as sunscreen agents THE PROCTER & GAMBLE COMPANY (US) 1995-08-08 US disclosed
US-5424421-A Synthesis of carminic acid and principal intermediates EUROPEAN COLOUR PLC (GB) 1995-06-13 US disclosed
US-5384115-A Photoprotection compositions comprising a radical scavenging compound and an anti-inflammatory agent THE PROCTER & GAMBLE COMPANY (US) 1995-01-24 US disclosed
EP-0602027-A1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES. EUROP COLOUR PLC (GB) 1994-06-22 EP disclosed
WO-1992001664-A1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROPEAN COLOUR PLC (GB) 1992-02-06 WO disclosed
US-4869897-A SUNCREEN AGENTS THE PROCTER & GAMBLE COMPANY (US) 1989-09-26 US disclosed