SCHEMBL8976444

SCHEMBL8976444

COc1cc2c(OC)c3c(OC)ccc(OC)c3c(OC)c2c(C)c1C(=O)OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCZ Q05513 1/20 0.45
KMT2A Q03164 3/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
PDE4B Q07343 1/20 0.42
PDE4D Q08499 1/20 0.42
PDE7A Q13946 1/20 0.42
PDE3A Q14432 1/20 0.42
PDE7B Q9NP56 1/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
MAPK1 P28482 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PRNP P04156 1/20 0.40
PDE1C Q14123 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A3 Q01959 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8952310 0.86 MAPT (0.47) SMN1; SMN2L3MBTL1
SCHEMBL8976115 0.81 CYP3A4 (0.43) POLBPDE3AMAPK1L3MBTL1PDE1C
SCHEMBL8976463 0.81 KDM4E (0.40) KMT2AMEN1NPC1SMN1; SMN2MAPK1
SCHEMBL8976409 0.80 KDM4E (0.42) KMT2AMEN1POLBATML3MBTL1
SCHEMBL8952390 0.78 CYP3A4 (0.46) KMT2ARAB9ASMN1; SMN2MAPK1HSD17B10
SCHEMBL31643516 0.77 TDP1 (0.49) PRKCZKMT2AMEN1POLBNPC1
SCHEMBL8952362 0.77 LMNA (0.47) KMT2AMEN1SMN1; SMN2L3MBTL1HSD17B10
SCHEMBL31643711 0.75 PRKCZ (0.45) PRKCZKMT2AMEN1POLBPDE4B
SCHEMBL8976225 0.75 PRKCZ (0.47) PRKCZKMT2AMEN1POLBNPC1
SCHEMBL20620358 0.75 RAB9A (0.53) PRKCZKMT2APOLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602027-B1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROP COLOUR PLC (GB) 1996-03-27 EP disclosed
US-5424421-A Synthesis of carminic acid and principal intermediates EUROPEAN COLOUR PLC (GB) 1995-06-13 US disclosed
EP-0602027-A1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES. EUROP COLOUR PLC (GB) 1994-06-22 EP disclosed
WO-1992001664-A1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROPEAN COLOUR PLC (GB) 1992-02-06 WO disclosed