Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976846 | 0.82 | CYP1A2 (0.35) | NPC1L3MBTL1MAPK1TSHRCYP2C19 | |
| SCHEMBL8976816 | 0.78 | CA1 (0.36) | APEX1NPC1L3MBTL1MAPK1CA1 | |
| SCHEMBL8976855 | 0.73 | ALDH1A1 (0.35) | L3MBTL1TSHRCA2CYP2C19ALDH1A1 | |
| SCHEMBL17796048 | 0.70 | APEX1 (0.35) | APEX1CA1CA2CA9CYP2C19 | |
| SCHEMBL9240542 | 0.70 | APEX1 (0.38) | APEX1NPC1L3MBTL1TSHRKIF11 | |
| SCHEMBL6165769 | 0.70 | APEX1 (0.38) | APEX1NPC1L3MBTL1TSHRKIF11 | |
| SCHEMBL30491175 | 0.70 | APEX1 (0.38) | APEX1NPC1L3MBTL1TSHRKIF11 | |
| SCHEMBL28425202 | 0.69 | CA1 (0.44) | APEX1NPC1L3MBTL1MAPK1TSHR | |
| SCHEMBL6819958 | 0.69 | APEX1 (0.40) | APEX1NPC1L3MBTL1MAPK1TSHR | |
| SCHEMBL28445506 | 0.69 | APEX1 (0.40) | APEX1NPC1L3MBTL1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534646-A | OXIDATION RESISTANCE FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | claimed |
| US-5534646-A | OXIDATION RESISTANCE FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |