SCHEMBL6819958

SCHEMBL6819958

CC(C)(C)c1ccc(OP(c2ccccc2)c2ccccc2)c(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.40
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
NPC1 O15118 1/20 0.35
PLA2G1B P04054 1/20 0.35
NFKB1 P19838 1/20 0.35
CASP3 P42574 1/20 0.35
RAB9A P51151 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
ATG4B Q9Y4P1 1/20 0.35
CYP2C19 P33261 2/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7615315 0.98 APEX1 (0.39) APEX1CA1CA2CA9ALDH1A1
SCHEMBL9402856 0.91 RXRA (0.37) APEX1CA1CA2CA9ALDH1A1
SCHEMBL7115234 0.89 APEX1 (0.39) APEX1CA1CA2CA9ALDH1A1
SCHEMBL31556870 0.89 APEX1 (0.39) APEX1CA1CA2CA9ALDH1A1
SCHEMBL9402893 0.86 APEX1 (0.34) APEX1CA1CA2CA9KDM4E
SCHEMBL7615609 0.86 APEX1 (0.34) APEX1CA1CA2CA9CYP2C19
SCHEMBL2960192 0.86 APEX1 (0.40) APEX1CA1CA2CA9ALDH1A1
SCHEMBL28363499 0.82 TDP1 (0.42) CA2ALDH1A1CYP2C19CYP1A2TSHR
SCHEMBL9299329 0.82 APEX1 (0.36) APEX1CA1CA2CA9ALDH1A1
SCHEMBL7621153 0.81 CA1 (0.33) APEX1CA1CA2CA9KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6168893-B1 AN ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR WHOSE STABILITY HAS BEEN IMPROVED BY INCORPORATING AN ARYLOXYDIARYLPHOSPHINE COMPOUND INTO A LAYER HAVING CHARGE TRANSPORT MATERIAL FUJI ELECTRIC IMAGING DEVICE CO., LTD. (JP) 2001-01-02 US claimed
CN-101466789-B Resin composition TEIJIN CHEMICALS LTD 2012-08-29 CN disclosed
CN-101434749-B Polycarbonate resin composition TEIJIN CHEMICALS LTD 2012-06-20 CN disclosed
CN-101522801-A Polycarbonate resin composition and molded article thereof TEIJIN CHEMICALS LTD (JP) 2009-09-02 CN disclosed
CN-101519528-A Polycarbonate resin composition with superior appearance TEIJIN CHEMICALS LTD 2009-09-02 CN disclosed
CN-101472972-A Polycarbonate and method for producing same TEIJIN CHEMICALS LTD (JP) 2009-07-01 CN disclosed
CN-101466789-A Resin composition TEIJIN CHEMICALS LTD (JP) 2009-06-24 CN disclosed
CN-101434749-A Polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 2009-05-20 CN disclosed
CN-101434750-A Polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 2009-05-20 CN disclosed
CN-101429330-A Resin composition TEIJIN CHEMICALS LTD (JP) 2009-05-13 CN disclosed
CN-101423655-A Antiflaming optical diffusion polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 2009-05-06 CN disclosed
CN-101412844-A Flame-retardant polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 2009-04-22 CN disclosed
US-20080057227-A1 Manufacturing method of cellulose acylate film, cellulose acylate film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2008-03-06 US disclosed
US-20080057227-A1 Manufacturing method of cellulose acylate film, cellulose acylate film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2008-03-06 US disclosed
US-6720121-B2 PHOTOSENSITIVE LAYER COMPRISING TRI(4- NITROPHENYL) PHOSPHATE FUJI ELECTRIC IMAGING DEVICE CO. LTD. (JP) 2004-04-13 US disclosed
US-6613488-B1 Metal-free- or titanyloxy- phthalocyanine compound and phthalimide salt FUJI ELECTRIC IMAGING DEVICES CO., LTD. (JP) 2003-09-02 US disclosed
US-20020172878-A1 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2002-11-21 US disclosed
WO-2002044188-A1 PALLADACYCLIC COMPOUNDS CONTAINING PHOSPHORUS DONOR LIGANDS, THE LIGANDS AND THE USE OF THE COMPOUNDS IN C-C COUPLING REACTIONS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2002-06-06 WO disclosed
US-6168893-B1 AN ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR WHOSE STABILITY HAS BEEN IMPROVED BY INCORPORATING AN ARYLOXYDIARYLPHOSPHINE COMPOUND INTO A LAYER HAVING CHARGE TRANSPORT MATERIAL FUJI ELECTRIC IMAGING DEVICE CO., LTD. (JP) 2001-01-02 US disclosed