SCHEMBL8976824

SCHEMBL8976824

CCCCCCCN1C(=O)CN(c2ccccc2)C1=S

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MAPT P10636 1/20 0.51
ATM Q13315 1/20 0.51
FAAH O00519 1/20 0.48
CNR2 P34972 3/20 0.48
KMT2A Q03164 1/20 0.48
CNR1 P21554 1/20 0.48
GRM2 Q14416 4/20 0.46
CES1 P23141 2/20 0.44
CDC25A P30304 1/20 0.44
MGLL Q99685 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11069122 0.95 NPC1 (0.58) NPC1RAB9ASMN1; SMN2MAPTATM
SCHEMBL10383197 0.83 NPC1 (0.50) NPC1RAB9ASMN1; SMN2MAPTATM
SCHEMBL11089881 0.80 RAB9A (0.50) NPC1RAB9ASMN1; SMN2MAPTATM
SCHEMBL10797889 0.75 NPC1 (0.68) NPC1RAB9ASMN1; SMN2MAPTATM
SCHEMBL11614288 0.75 SMN1; SMN2 (0.51) NPC1RAB9ASMN1; SMN2GRM2
SCHEMBL14560510 0.75 NPC1 (0.51) NPC1RAB9ASMN1; SMN2MAPTFAAH
SCHEMBL11067037 0.75 GSK3A (0.51) NPC1RAB9ASMN1; SMN2MAPTKMT2A
SCHEMBL219908 0.74 MGLL (0.43) NPC1RAB9ASMN1; SMN2MAPTFAAH
SCHEMBL5570285 0.74 MGLL (0.50) MAPTFAAHCNR2KMT2ACNR1
SCHEMBL11066753 0.74 NPC1 (0.54) NPC1RAB9ASMN1; SMN2MAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0384633-B1 Radiographic elements with selected speed relationships EASTMAN KODAK CO (US) 1996-04-24 EP disclosed
EP-0313474-B1 AN OPTICAL ARTICLE EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-23 EP disclosed
EP-0313475-B1 AN OPTICAL ARTICLE CONTAINING A TRANSMISSION MEDIUM EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-23 EP disclosed
EP-0313476-B1 AN OPTICAL ARTICLE CONTAINING A POLYMERIC MATRIX EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-23 EP disclosed
EP-0341566-B1 DYE SENSITIZED PHOTOGRAPHIC IMAGING SYSTEMS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-23 EP disclosed
EP-0281381-B1 ELECTROLUMINESCENT DEVICE WITH MODIFIED THIN FILM LUMINESCENT ZONE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-07-15 EP disclosed
US-5021327-A Medical diagnosis EASTMAN KODAK COMPANY (US) 1991-06-04 US disclosed
US-4997750-A Reducing crossover in double coated x-ray film EASTMAN KODAK COMPANY (US) 1991-03-05 US disclosed
US-4973694-A FLUORESCENT DYES, FREE RADICAL POLYMERIZATION INITIATORS EASTMAN KODAK COMPANY (US) 1990-11-27 US disclosed
EP-0276566-B1 RADIOGRAPHIC ELEMENT EXHIBITING REDUCED CROSSOVER EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-10-24 EP disclosed
US-4792208-A POLAR ALIGNED NONCENTROSYMMETRIC MOLECULAR DIPOLES; SULFONYL MOIETY AS ELECTRON ACCEPTOR EASTMAN KODAK COMPANY (US) 1988-12-20 US disclosed
US-4769292-A Electroluminescent device with modified thin film luminescent zone EASTMAN KODAK COMPANY (US) 1988-09-06 US disclosed
US-4743531-A PHOTORESISTS EASTMAN KODAK COMPANY (US) 1988-05-10 US disclosed
US-4743529-A PRINTED CIRCUITS EASTMAN KODAK COMPANY (US) 1988-05-10 US disclosed
US-4743528-A Enhanced imaging composition containing an azinium activator EASTMAN KODAK COMPANY (US) 1988-05-10 US disclosed
US-4743530-A FILM FORMER, QUATERNIZED AZINIUM SALT ACTIVATOR, PHOTOSENSITIZER DYE EASTMAN KODAK COMPANY (US) 1988-05-10 US disclosed
EP-0111919-B1 MULTICOLOR PHOTOGRAPHIC ELEMENTS CONTAINING SILVER IODIDE GRAINS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-04-29 EP disclosed
US-4520098-A CONTAINING FINE IODIDE SILVER HALIDE PARTICLES IN CONCENTRATION CAPABLE OF BEING DISSOLVED OUT EASTMAN KODAK COMPANY (US) 1985-05-28 US disclosed
US-4490458-A Multicolor photographic elements containing silver iodide grains EASTMAN KODAK COMPANY (US) 1984-12-25 US disclosed
US-4439520-A Sensitized high aspect ratio silver halide emulsions and photographic elements EASTMAN KODAK COMPANY (US) 1984-03-27 US disclosed