Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 13/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.71 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.71 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.60 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976841 | 1.00 | CHRM1 (0.71) | CHRM1CHRM2CHRM4CHRM3ADRA1D | |
| SCHEMBL8976790 | 0.85 | CHRM1 (0.64) | CHRM1CHRM2CHRM4CHRM3ADRA1D | |
| SCHEMBL8976895 | 0.85 | OPRM1 (0.72) | CHRM1CHRM2CHRM4CHRM3ADRA1D | |
| SCHEMBL8976901 | 0.85 | OPRM1 (0.72) | CHRM1CHRM2CHRM4CHRM3ADRA1D | |
| SCHEMBL8976793 | 0.85 | CHRM1 (0.64) | CHRM1CHRM2CHRM4CHRM3ADRA1D | |
| SCHEMBL3895786 | 0.84 | CHRM1 (0.92) | CHRM1CHRM2CHRM4CHRM3ADRA1D | |
| SCHEMBL8863420 | 0.84 | CHRM1 (0.76) | CHRM1CHRM2CHRM4CHRM3ADRA1D | |
| SCHEMBL8863418 | 0.84 | CHRM1 (0.76) | CHRM1CHRM2CHRM4CHRM3ADRA1D | |
| SCHEMBL8863399 | 0.84 | CHRM1 (0.76) | CHRM1CHRM2CHRM4CHRM3ADRA1D | |
| SCHEMBL8863397 | 0.84 | CHRM1 (0.76) | CHRM1CHRM2CHRM4CHRM3ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996013262-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1996-05-09 | — | — | WO | claimed |
| US-5574044-A | BENZIMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF MYOPIA | MERCK & CO., INC. (US) | 1996-11-12 | — | — | US | disclosed |
| WO-1996013262-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1996-05-09 | — | — | WO | disclosed |