Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.72 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.72 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.54 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976901 | 1.00 | OPRM1 (0.72) | OPRM1OPRL1OPRK1ADRA1DADRA1A | |
| SCHEMBL5771940 | 0.90 | OPRM1 (0.88) | OPRM1OPRL1OPRK1ADRA1DADRA1A | |
| SCHEMBL8976841 | 0.85 | CHRM1 (0.71) | OPRM1OPRL1OPRK1ADRA1DADRA1A | |
| SCHEMBL8976844 | 0.85 | CHRM1 (0.71) | OPRM1OPRL1OPRK1ADRA1DADRA1A | |
| SCHEMBL6591096 | 0.85 | OPRM1 (0.97) | OPRM1OPRL1OPRK1ADRA1DADRA1A | |
| SCHEMBL14186018 | 0.84 | OPRM1 (1.00) | OPRM1OPRL1OPRK1CYP2D6CYP2C9 | |
| SCHEMBL4922697 | 0.84 | OPRM1 (1.00) | OPRM1OPRL1OPRK1CYP2D6CYP2C9 | |
| SCHEMBL4913077 | 0.84 | OPRM1 (1.00) | OPRM1OPRL1OPRK1CYP2D6CYP2C9 | |
| SCHEMBL4921324 | 0.84 | OPRM1 (1.00) | OPRM1OPRL1OPRK1CYP2D6CYP2C9 | |
| SCHEMBL6585522 | 0.84 | OPRM1 (1.00) | OPRM1OPRL1OPRK1CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996013262-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1996-05-09 | — | — | WO | claimed |
| US-5574044-A | BENZIMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF MYOPIA | MERCK & CO., INC. (US) | 1996-11-12 | — | — | US | disclosed |