Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976796 | 0.85 | GABRA1 (0.30) | — | |
| SCHEMBL8976855 | 0.75 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL10789897 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL10904840 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL11647740 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL28412493 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL5857102 | 0.69 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL10567279 | 0.68 | CYP3A4 (0.42) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL2868169 | 0.67 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL21500784 | 0.67 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534646-A | OXIDATION RESISTANCE FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |