SCHEMBL897715

SCHEMBL897715

C=Cc1ccc(C(C)(C)C(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
CYP1A2 P05177 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 2/20 0.39
TAS1R3 Q7RTX0 2/20 0.39
TAS1R1 Q7RTX1 2/20 0.39
APP P05067 1/20 0.38
CYP2C19 P33261 1/20 0.38
AKR1C3 P42330 2/20 0.37
AKR1C2 P52895 2/20 0.37
CYP2C9 P11712 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MAP4K4 O95819 1/20 0.35
TRPV1 Q8NER1 1/20 0.35
ESRRG P62508 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9680278 0.86 ALDH1A1 (0.46) ALDH1A1CYP1A2TDP1MAPTKMT2A
Acetic Acid SCHEMBL28494888 0.83 RORC (0.37) ALDH1A1CYP1A2TDP1MAPTKMT2A
SCHEMBL3497043 0.82 MAPT (0.52) ALDH1A1MAPTKMT2ATSHRAPP
SCHEMBL13101222 0.82 TDP1 (0.39) ALDH1A1CYP1A2TDP1MAPTKMT2A
SCHEMBL5326924 0.82 ALDH1A1 (0.48) ALDH1A1CYP1A2MAPTKMT2AAPP
SCHEMBL21649707 0.79 CNR1 (0.44) ALDH1A1CYP1A2TDP1TAS1R3TAS1R1
SCHEMBL8761784 0.79 ALDH1A1 (0.48) ALDH1A1CYP1A2TDP1TSHRTAS1R3
SCHEMBL7858654 0.78 ALDH1A1 (0.38) ALDH1A1CYP1A2TDP1MAPTKMT2A
SCHEMBL127443 0.77 MAPT (0.43) ALDH1A1MAPTKMT2AAPPAKR1C3
SCHEMBL4664901 0.76 SRD5A2 (0.54) ALDH1A1CYP1A2TDP1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115838458-B Novel polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2025-03-11 CN claimed
CN-115894814-B Novel polycarboxylic acid slump retaining agent and preparation method thereof 科之杰新材料集团有限公司 2025-02-18 CN claimed
CN-118405870-B Early strength water reducer and preparation method and application thereof 山西铁力建材有限公司 2024-09-24 CN claimed
CN-118405870-A Early strength water reducer and preparation method and application thereof 山西铁力建材有限公司 2024-07-30 CN claimed
CN-114709406-B Sulfur-rich copolymer material, lithium sulfur battery positive electrode material, and preparation methods and applications thereof 中国电建集团成都勘测设计研究院有限公司 2023-07-25 CN claimed
CN-115894814-A Novel polycarboxylic acid slump retaining agent and preparation method thereof 科之杰新材料集团有限公司 2023-04-04 CN claimed
CN-115838458-A Novel polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2023-03-24 CN claimed
CN-115835742-A High-quality tin-based perovskite thin film, preparation method thereof and photoelectric device 华中科技大学 2023-03-21 CN claimed
CN-114709406-A Sulfur-rich copolymer material, lithium-sulfur battery positive electrode material, and preparation methods and applications thereof 中国电建集团成都勘测设计研究院有限公司 2022-07-05 CN claimed
US-12297323-B2 Polysiloxane vinylic crosslinkers with high refractive index ALCON INC. (CH) 2025-05-13 US disclosed
EP-4314118-B1 POLYSILOXANE VINYLIC CROSSLINKERS WITH HIGH REFRACTIVE INDEX ALCON INC (CH) 2025-04-30 EP disclosed
CN-115838458-B Novel polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2025-03-11 CN disclosed
CN-115894814-B Novel polycarboxylic acid slump retaining agent and preparation method thereof 科之杰新材料集团有限公司 2025-02-18 CN disclosed
CN-118405870-B Early strength water reducer and preparation method and application thereof 山西铁力建材有限公司 2024-09-24 CN disclosed
CN-102459172-A Tetracyclic compounds CHUGAI PHARMACEUTICAL CO LTD 2012-05-16 CN disclosed
EP-2441753-A1 TETRACYCLIC COMPOUND Chugai Seiyaku Kabushiki Kaisha (JP) 2012-04-18 EP disclosed
EP-2441753-A1 TETRACYCLIC COMPOUND Chugai Seiyaku Kabushiki Kaisha (JP) 2012-04-18 EP disclosed
US-20120083488-A1 TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA 2012-04-05 US disclosed
US-20120083488-A1 TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA 2012-04-05 US disclosed
WO-2010143664-A1 TETRACYCLIC COMPOUND 中外製薬株式会社 (JP) 2010-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120083488-A1 TETRACYCLIC COMPOUND ALK, TTR, ACVR1 ALDH1A1 1165/4885CYP1A2 2961/4885TDP1 361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.