Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497043 | 0.92 | MAPT (0.52) | SRD5A2HDAC1MAPTKMT2ATSHR | |
| SCHEMBL1107163 | 0.83 | TSHR (0.50) | SRD5A2LMNAHDAC1SMN1; SMN2MAPT | |
| SCHEMBL1819260 | 0.83 | ESR1 (0.54) | LMNATYRMAPTKMT2ATSHR | |
| SCHEMBL6571 | 0.82 | MAPT (0.67) | HDAC1CYP1A2MAPTKMT2ATSHR | |
| SCHEMBL127443 | 0.81 | MAPT (0.43) | SRD5A2HDAC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9130779 | 0.81 | SRD5A2 (0.61) | SRD5A2TYRSMN1; SMN2RARBRARG | |
| SCHEMBL262460 | 0.81 | MAPT (0.48) | LMNAMAPTKMT2ATDP1EPHX2 | |
| SCHEMBL697244 | 0.81 | MAP4K4 (0.55) | SMN1; SMN2CYP1A2MAPTKMT2ATSHR | |
| SCHEMBL1626471 | 0.81 | APP (0.62) | SRD5A2LMNACYP1A2MAPTKMT2A | |
| SCHEMBL6673990 | 0.81 | SRD5A2 (0.50) | SRD5A2LMNAHDAC1TYRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787824-B2 | Titanium heterometallic metal-organic solids, method for obtaining them and their uses | UNIVERSITAT DE VALÈNCIA (ES) | 2023-10-17 | — | — | US | disclosed |
| CN-111417707-A | Storage-stable enzyme preparations, their production and use | 巴斯夫欧洲公司 | 2020-07-14 | — | — | CN | disclosed |
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | GODEL THIERRY | 2008-06-05 | — | — | US | disclosed |
| US-7135487-B2 | such as N-2-(4-Bromophenyl)propyl methanesulfonamide; sulfonamidation of the amine; glutamate receptor potentiators | ELI LILLY AND COMPANY (US) | 2006-11-14 | — | — | US | disclosed |
| EP-1689729-A1 | TETRONIC AND TETRAMIC ACIDS AS INHIBITORS OF BETA-SECREASE | F. Hoffmann-La Roche AG (CH) | 2006-08-16 | — | — | EP | disclosed |
| US-20060030599-A1 | SULPHONAMIDE DERIVATIVES | ARNOLD MACKLIN B | 2006-02-09 | — | — | US | disclosed |
| WO-2005058857-A1 | TETRONIC AND TETRAMIC ACIDS AS INHIBITORS OF BETA-SECREASE | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-30 | — | — | WO | disclosed |
| US-20050119329-A1 | Tetronic and tetramic acids | HOFFMANN-LA ROCHE INC. | 2005-06-02 | — | — | US | disclosed |
| EP-1528055-A2 | Sulphonamide Derivatives | Eli Lilly & Company (US) | 2005-05-04 | — | — | EP | disclosed |
| US-20040097499-A1 | Amide, carbamate, and urea derivatives | ARNOLD MACKLIN BRIAN (US) | 2004-05-20 | — | — | US | disclosed |
| US-20020002158-A1 | Sulphonamide derivatives | ARNOLD MACKLIN B (US) | 2002-01-03 | — | — | US | disclosed |
| US-6303816-B1 | Sulphonamide derivatives | ELI LILLY AND COMPANY | 2001-10-16 | — | — | US | disclosed |
| US-6075120-A | A HETERODIMERIC PEPTIDE MODULATOR; FOR THE TREATMENT OF ASTHMA; FOR THE TREATMENT OF PAIN; ANTIINFLAMMATORY AGENTS | CORTECH, INC. (US) | 2000-06-13 | — | — | US | disclosed |
| CN-1251523-A | Sulfonamide derivatives | LILLY CO ELI (US) | 2000-04-26 | — | — | CN | disclosed |
| EP-0976744-A1 | Amide, carbamate, and urea derivatives having glutamate receptor function potentiating activity | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| US-5863899-A | ANALGESICS AND ANTIINFLAMMATORY AGENT; A MORPHINE OR DERIVATIVE IS ATTACHED TO BRANDYKININ ANTAGONIST PEPTIDE BY MALEIMIDO OR AMINO ACID ANALOG LINKER | CORTECH, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| EP-0860428-A2 | Sulphonamide derivatives | ELI LILLY AND COMPANY (US) | 1998-08-26 | — | — | EP | disclosed |
| EP-0671941-A4 | BRADYKININ ANTAGONISTS. | CORTECH INC (US) | 1996-05-29 | — | — | EP | disclosed |
| EP-0671941-A1 | BRADYKININ ANTAGONISTS | CORTECH, INC. (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994011021-A1 | BRADYKININ ANTAGONISTS | CORTECH, INC. (US) | 1994-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030599-A1 | SULPHONAMIDE DERIVATIVES | GRIN2C, GLRA2, GLRA1 | SRD5A2 1610/4885LMNA 3909/4885HDAC1 1292/4885 |
| US-20020002158-A1 | Sulphonamide derivatives | GRIN2C, GRM1, GRM3 | SRD5A2 833/4885LMNA 2852/4885HDAC1 514/4885 |
| US-20040097499-A1 | Amide, carbamate, and urea derivatives | GRIN2A, GLUL, GRIK5 | SRD5A2 4390/4885LMNA 4726/4885HDAC1 233/4885 |
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | BACE1, PSEN1, BACE2 | SRD5A2 2942/4885LMNA 1625/4885HDAC1 89/4885 |
| US-20050119329-A1 | Tetronic and tetramic acids | BACE1, PSEN1, BACE2 | SRD5A2 2942/4885LMNA 1625/4885HDAC1 89/4885 |
| US-11787824-B2 | Titanium heterometallic metal-organic solids, method for obtaining them and their uses | FTO, TDO2, PICALM | SRD5A2 3163/4885LMNA 3973/4885HDAC1 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.