Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977089 | 0.85 | KDM4E (0.33) | PDE4BPDE4DKDM4EGAATSHR | |
| SCHEMBL8977153 | 0.84 | KDM4E (0.38) | PDE4BPDE4DKDM4EGAATSHR | |
| SCHEMBL8995696 | 0.78 | GABRP (0.37) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL8846408 | 0.73 | KDM4E (0.37) | PDE4BPDE4DKDM4EGAATSHR | |
| SCHEMBL8995714 | 0.71 | HCAR2 (0.41) | KDM4EGAAMEN1KMT2A | |
| SCHEMBL16191206 | 0.71 | KDM4E (0.36) | PDE4BPDE4DKDM4EGAATSHR | |
| SCHEMBL29458340 | 0.69 | KDM4E (0.35) | PDE4BPDE4DKDM4EGAATSHR | |
| SCHEMBL271102 | 0.69 | KDM4E (0.35) | PDE4BPDE4DKDM4EGAATSHR | |
| SCHEMBL27699173 | 0.69 | KDM4E (0.35) | PDE4BPDE4DKDM4EGAATSHR | |
| SCHEMBL9784563 | 0.69 | HCAR2 (0.38) | PDE4BPDE4DKDM4ESMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461403-B1 | Process for the preparation of dialkyl pyridine-2,3-dicarboxylate and derivatives thereof from dialkyl dichlorosucciante | AMERICAN CYANAMID CO (US) | 1996-08-28 | — | — | EP | claimed |
| EP-0560019-B1 | Process for the preparation of dialkyl 2,3-pyridinedicarboxylate and derivatives thereof from an alpha, beta-unsaturated oxime and an aminobutenedioate | AMERICAN CYANAMID CO (US) | 1996-04-24 | — | — | EP | claimed |