Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784571 | 0.85 | HCAR2 (0.41) | HCAR2DPP4DPP8DPP9ADORA3 | |
| SCHEMBL8995696 | 0.85 | GABRP (0.37) | HCAR2DPP4DPP8DPP9ADORA3 | |
| SCHEMBL9784563 | 0.79 | HCAR2 (0.38) | HCAR2DPP4DPP8DPP9ADORA3 | |
| SCHEMBL29188835 | 0.79 | GABRP (0.33) | HCAR2DPP4DPP8DPP9ADORA3 | |
| SCHEMBL31436370 | 0.78 | HCAR2 (0.41) | HCAR2DPP4DPP8DPP9ADORA3 | |
| SCHEMBL8995682 | 0.76 | KMO (0.34) | HCAR2DPP4DPP8DPP9ADORA3 | |
| SCHEMBL30968740 | 0.76 | HCAR2 (0.33) | HCAR2DPP4DPP8DPP9ADORA3 | |
| SCHEMBL11375262 | 0.75 | ALDH1A1 (0.40) | HCAR2DPP4DPP8DPP9ADORA3 | |
| SCHEMBL8977153 | 0.75 | KDM4E (0.38) | HCAR2KDM4EGAA | |
| SCHEMBL29774205 | 0.74 | TDP1 (0.39) | HCAR2MEN1KMT2ANPC1FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480002-A | High-selectivity synthesis method of imazamox intermediate diethyl 5-bromomethyl-2, 3-pyridine dicarboxylic acid | 湖北三峡实验室 | 2024-08-13 | — | — | CN | claimed |
| EP-0461403-B1 | Process for the preparation of dialkyl pyridine-2,3-dicarboxylate and derivatives thereof from dialkyl dichlorosucciante | AMERICAN CYANAMID CO (US) | 1996-08-28 | — | — | EP | claimed |
| CN-222076592-U | Acidification kettle for producing 5-methyl-pyridine-2, 3-dicarboxylic acid diethyl ester | 苏州嘉实稳博新能源有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118480002-A | High-selectivity synthesis method of imazamox intermediate diethyl 5-bromomethyl-2, 3-pyridine dicarboxylic acid | 湖北三峡实验室 | 2024-08-13 | — | — | CN | disclosed |
| CN-221385246-U | Rectifying device for producing 5-methyl-pyridine-2, 3-diethyl dicarboxylate | 武威昌鸿科技有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-220939170-U | Rectifying device for production and processing of 5-methyl-pyridine-2, 3-dicarboxylic acid diethyl ester | 武威昌鸿科技有限公司 | 2024-05-14 | — | — | CN | disclosed |
| EP-4001266-A2 | PROCESS FOR PREPARING METHOXY METHYL PYRIDINE DICARBOXYLATE | Adama Agan Ltd. (IL) | 2022-05-25 | — | — | EP | disclosed |
| US-10669254-B2 | Process for preparing methoxy methyl pyridine dicarboxylate | ADAMA AGAN LTD. (IL) | 2020-06-02 | — | — | US | disclosed |
| EP-3541787-A1 | PROCESS FOR PREPARING METHOXY METHYL PYRIDINE DICARBOXYLATE | Adama Agan Ltd. (IL) | 2019-09-25 | — | — | EP | disclosed |
| US-20190276427-A1 | PROCESS FOR PREPARING METHOXY METHYL PYRIDINE DICARBOXYLATE | ADAMA AGAN LTD. (IL) | 2019-09-12 | — | — | US | disclosed |
| WO-2018091964-A1 | PROCESS FOR PREPARING METHOXY METHYL PYRIDINE DICARBOXYLATE | ADAMA AGAN LTD. (IL) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669254-B2 | Process for preparing methoxy methyl pyridine dicarboxylate | MCCC2, C5, KDM4C | HCAR2 612/4885DPP4 1363/4885DPP8 3961/4885 |
| US-20190276427-A1 | PROCESS FOR PREPARING METHOXY METHYL PYRIDINE DICARBOXYLATE | MCCC2, C5, KDM4C | HCAR2 612/4885DPP4 1363/4885DPP8 3961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.