SCHEMBL8977183

SCHEMBL8977183

O=C(C=Cc1ccc(O)cc1)c1ccc([N+](=O)[O-])c(Cl)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.73
NPSR1 Q6W5P4 3/20 0.73
RAB9A P51151 3/20 0.73
MITF O75030 1/20 0.73
RECQL P46063 1/20 0.73
ALDH1A1 P00352 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
MAOB P27338 4/20 0.57
CXCL12 P48061 1/20 0.57
F3 P13726 1/20 0.56
BACE1 P56817 2/20 0.56
XDH P47989 1/20 0.56
HSPD1 P10809 1/20 0.55
HSPE1 P61604 1/20 0.55
MAOA P21397 2/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
MAPK1 P28482 2/20 0.54
HTT P42858 2/20 0.54
LMNA P02545 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8977182 1.00 MAPT (0.73) MAPTNPSR1RAB9AMITFRECQL
SCHEMBL8965252 0.92 MAPT (0.81) MAPTNPSR1RAB9AMITFRECQL
SCHEMBL8965249 0.92 MAPT (0.81) MAPTNPSR1RAB9AMITFRECQL
SCHEMBL25217899 0.84 MAPT (1.00) MAPTNPSR1RAB9AMITFRECQL
SCHEMBL25201160 0.84 MAPT (1.00) MAPTNPSR1RAB9AMITFRECQL
SCHEMBL7306057 0.82 F3 (0.69) MAPTNPSR1RAB9AMITFRECQL
SCHEMBL7312933 0.82 F3 (0.69) MAPTNPSR1RAB9AMITFRECQL
SCHEMBL8965115 0.81 MAPT (0.64) MAPTNPSR1RAB9AMITFRECQL
SCHEMBL8965711 0.79 MAPT (0.69) MAPTNPSR1RAB9AMITFRECQL
SCHEMBL8965713 0.79 MAPT (0.69) MAPTNPSR1RAB9AMITFRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0428398-B1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-04-03 EP claimed
EP-0428398-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-22 EP claimed
EP-0428398-B1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-04-03 EP disclosed
US-5110706-A Photoresists for highly reflective substrates JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-05-05 US disclosed
EP-0428398-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-22 EP disclosed