Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977282 | 0.94 | KDM1A (0.38) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL15906653 | 0.76 | NOTUM (0.47) | PTGS2PTGS1ATM | |
| SCHEMBL8977320 | 0.76 | NPC1 (0.41) | NPC1RAB9ADRD2ATMMAOB | |
| SCHEMBL1066184 | 0.75 | KDM1A (0.48) | PTGS2PTGS1DRD2HTR1AHTR2A | |
| SCHEMBL18161913 | 0.75 | KDM1A (0.48) | PTGS2PTGS1DRD2HTR1AHTR2A | |
| SCHEMBL8396919 | 0.74 | PTGS2 (0.38) | PTGS2PTGS1NPC1RAB9ADRD2 | |
| SCHEMBL8977249 | 0.73 | NPC1 (0.41) | PTGS2PTGS1NPC1RAB9ADRD2 | |
| SCHEMBL14064094 | 0.73 | ESR2 (0.59) | PTGS2PTGS1NPC1RAB9ADRD2 | |
| SCHEMBL12056676 | 0.73 | PTGS2 (0.48) | PTGS2PTGS1NPC1RAB9ADRD2 | |
| SCHEMBL13628947 | 0.73 | ESR2 (0.59) | KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523439-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0696592-A1 | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |