Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977379 | 0.95 | DRD2 (0.43) | NPC1RAB9ADRD2ADRA1DADRA1A | |
| SCHEMBL7757153 | 0.79 | DRD2 (0.35) | NPC1RAB9ADRD2SMN1; SMN2MAOA | |
| SCHEMBL8977348 | 0.78 | NPC1 (0.38) | NPC1RAB9A | |
| SCHEMBL8977338 | 0.78 | NPC1 (0.38) | NPC1RAB9A | |
| SCHEMBL8977220 | 0.76 | PTGS2 (0.38) | NPC1RAB9ADRD2MAOBATM | |
| SCHEMBL7757549 | 0.76 | SPHK1 (0.33) | NPC1RAB9ADRD2MAOAMAOB | |
| SCHEMBL15906653 | 0.71 | NOTUM (0.47) | CYP3A4CYP2C9ATM | |
| SCHEMBL26566340 | 0.70 | PTGS2 (0.43) | NPC1RAB9ADRD2CYP3A4 | |
| SCHEMBL15757454 | 0.70 | NPC1 (0.70) | NPC1RAB9ACYP1A2CYP2C19MAOB | |
| SCHEMBL8977301 | 0.70 | NFE2L2 (0.47) | DRD2ADRA1DADRA1AADRA1BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523439-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0696592-A1 | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |