Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977220 | 0.94 | PTGS2 (0.38) | KDM1ADRD2HTR2AHTR1ADRD3 | |
| Ammonia Solution, Strong SCHEMBL22408764 | 0.77 | KDM1A (0.46) | KDM1ADRD2HTR2AHTR1ADRD3 | |
| SCHEMBL779666 | 0.75 | ATM (0.46) | KDM1AHTR2AATMMAP1LC3BSLC6A2 | |
| SCHEMBL8977379 | 0.73 | DRD2 (0.43) | KDM1ADRD2ATM | |
| SCHEMBL24087487 | 0.73 | PTGS2 (0.48) | KDM1AHTR2AATMMAP1LC3BADRB2 | |
| SCHEMBL18805040 | 0.73 | ATM (0.45) | KDM1AATM | |
| SCHEMBL21581460 | 0.73 | KDM1A (0.43) | KDM1ADRD2HTR2AHTR1ADRD3 | |
| SCHEMBL126027 | 0.73 | ATM (0.45) | KDM1AATM | |
| SCHEMBL8596563 | 0.71 | KDM1A (0.41) | KDM1ADRD2HTR2AHTR1ADRD3 | |
| SCHEMBL8596561 | 0.71 | KDM1A (0.41) | KDM1ADRD2HTR2AHTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523439-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0696592-A1 | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |