Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977332 | 0.94 | OPRL1 (0.37) | GRIA1GRIA2GRIA3GRIA4CYP11B2 | |
| SCHEMBL8977372 | 0.81 | GRIA1 (0.35) | GRIA1GRIA2GRIA3GRIA4CYP11B2 | |
| SCHEMBL1193108 | 0.77 | ALDH1A1 (0.49) | CYP11B2CBFBKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8977368 | 0.75 | OPRL1 (0.37) | GRIA1GRIA2GRIA3GRIA4CYP11B2 | |
| SCHEMBL1440759 | 0.74 | ALDH1A1 (0.47) | GRIA1GRIA2GRIA3GRIA4CBFB | |
| SCHEMBL12844638 | 0.71 | FABP6 (0.43) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8470034 | 0.71 | CBFB (0.42) | CBFBKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8470028 | 0.71 | POLB (0.40) | CBFBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1193135 | 0.71 | MAPT (0.52) | GRIA1GRIA2GRIA3GRIA4CBFB | |
| SCHEMBL8210550 | 0.69 | EGLN1 (0.46) | CYP11B2KDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554631-A | ANTIULCER | IL-YANG PHARM. CO., LTD. (KR) | 1996-09-10 | — | — | US | disclosed |