Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 13/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977372 | 0.94 | GRIA1 (0.35) | OPRL1CYP11B2CBFBKDM4EALDH1A1 | |
| SCHEMBL8071082 | 0.82 | CYP19A1 (0.36) | OPRL1CYP11B2CBFBKDM4EALDH1A1 | |
| SCHEMBL8977332 | 0.81 | OPRL1 (0.37) | OPRL1CYP11B2CBFBKDM4EALDH1A1 | |
| SCHEMBL16134561 | 0.80 | KDM4E (0.38) | OPRL1CBFBKDM4EALDH1A1CYP1A2 | |
| SCHEMBL213270 | 0.77 | KDM4E (0.49) | OPRL1CYP11B2CBFBKDM4EALDH1A1 | |
| SCHEMBL8068945 | 0.77 | OPRL1 (0.51) | OPRL1ALDH1A1HSD17B10EGLN1 | |
| SCHEMBL8071080 | 0.76 | EGLN1 (0.52) | OPRL1HPGDEGLN1 | |
| SCHEMBL8977401 | 0.76 | OPRL1 (0.39) | OPRL1CBFBKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8070777 | 0.76 | EGLN1 (0.52) | OPRL1HPGDEGLN1 | |
| SCHEMBL8977340 | 0.75 | GRIA1 (0.35) | OPRL1CYP11B2CBFBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554631-A | ANTIULCER | IL-YANG PHARM. CO., LTD. (KR) | 1996-09-10 | — | — | US | disclosed |