Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015338 | 1.00 | P2RY14 (0.33) | P2RY14KDM1ACYP3A4CYP17A1CYP11B2 | |
| SCHEMBL8015335 | 1.00 | P2RY14 (0.33) | P2RY14KDM1ACYP3A4CYP17A1CYP11B2 | |
| SCHEMBL8393131 | 0.91 | KDM1A (0.36) | P2RY14KDM1ACYP3A4CYP17A1CYP11B2 | |
| SCHEMBL8977367 | 0.88 | USP5 (0.34) | KDM1ACCR2CYP2D6 | |
| SCHEMBL8977362 | 0.88 | USP5 (0.34) | KDM1ACCR2CYP2D6 | |
| SCHEMBL8977371 | 0.88 | USP5 (0.34) | KDM1ACCR2CYP2D6 | |
| SCHEMBL8768421 | 0.83 | PGR (0.39) | P2RY14KDM1ACYP3A4CYP17A1CYP11B2 | |
| SCHEMBL8768418 | 0.83 | PGR (0.39) | P2RY14KDM1ACYP3A4CYP17A1CYP11B2 | |
| SCHEMBL19850903 | 0.82 | KMT2A (0.39) | P2RY14KDM1ACYP3A4CYP17A1CYP11B2 | |
| SCHEMBL8024951 | 0.81 | ESR2 (0.42) | P2RY14KDM1ACYP3A4CYP17A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670322-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0670322-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |