Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034724 | 1.00 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL3208895 | 1.00 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL277984 | 0.96 | TSHR (0.41) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL9062589 | 0.83 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL9420314 | 0.81 | ALDH1A1 (0.35) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL585948 | 0.80 | TSHR (0.46) | MEN1KMT2ATSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL8815476 | 0.80 | TSHR (0.46) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL2796019 | 0.79 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL8966786 | 0.79 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL3286421 | 0.78 | ALDH1A1 (0.35) | TSHRTHRBALDH1A1TET2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556708-A | ADDITION-CONDENSATION GRAFT COPOLYMERIZATION IN WATER IN CARBON TETRACHLORIDE WITH A REDUCING AGENT | SARTORIUS AG (DE) | 1996-09-17 | — | — | US | disclosed |
| US-5547575-A | GRAFTING WITH UNSATURATED MONOMER USING SODIUM DITHIONATE IN AQUEOUS SOLUTION | SARTORIUS AG (DE) | 1996-08-20 | — | — | US | disclosed |
| US-5215692-A | Halogenation; dehalogenation; reduction | SARTORIUS AG (DE) | 1993-06-01 | — | — | US | disclosed |