Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 4/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977369 | 0.96 | MEN1 (0.48) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL3208895 | 0.96 | MEN1 (0.48) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL6034724 | 0.96 | MEN1 (0.48) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL351637 | 0.82 | TET2 (0.40) | TSHRTET2TET3TET1GRIK1 | |
| Di(Hydroxyethyl)Ether SCHEMBL8815476 | 0.79 | TSHR (0.46) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL585948 | 0.79 | TSHR (0.46) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL2219165 | 0.79 | CES2 (0.38) | TSHRTET2TET3TET1GRIK1 | |
| SCHEMBL3286421 | 0.77 | ALDH1A1 (0.35) | TSHRALDH1A1TET2TET3TET1 | |
| SCHEMBL4566618 | 0.77 | CES2 (0.32) | TET2TET3TET1GRIK1GRIK2 | |
| Itaconate SCHEMBL8899071 | 0.77 | HSD17B10 (0.54) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870236-B1 | NANOPARTICLE ENCAPSULATION TO TARGET G PROTEIN-COUPLED RECEPTORS IN ENDOSOMES | TAKEDA PHARMACEUTICALS CO (JP) | 2023-08-09 | — | — | EP | claimed |
| US-20230010001-A1 | PHOTOCROSSLINKED HYDROGELS BLENDED COMPOSITION, PREPARATION AND USE THEREOF | NATIONAL TAIWAN UNIVERSITY (TW) | 2023-01-12 | — | — | US | claimed |
| US-20220231333-A1 | QUASI-SOLID AND SOLID-STATE ELECTROLYTE FOR LITHIUM-ION AND LITHIUM METAL BATTERIES AND MANUFACTURING METHOD | HONEYCOMB BATTERY COMPANY | 2022-07-21 | — | — | US | claimed |
| WO-2022150849-A1 | FLAME-RESISTANT QUASI-SOLID AND SOLID-STATE ELECTROLYTE FOR LITHIUM-ION AND LITHIUM METAL BATTERIES AND PRODUCTION METHOD | GLOBAL GRAPHENE GROUP, INC. (US) | 2022-07-14 | — | — | WO | claimed |
| US-20220118159-A1 | ANTIOXIDANT-RELEASING VITREOUS SUBSTITUTES AND USES THEREOF | OHIO STATE INNOVATION FOUNDATION | 2022-04-21 | — | — | US | claimed |
| US-11267286-B2 | Rubber composition for tire tread and tire manufactured by using same | HANKOOK TIRE & TECHNOLOGY CO., LTD. (KR) | 2022-03-08 | — | — | US | claimed |
| US-20220031849-A1 | NANOPARTICLE ENCAPSULATION TO TARGET G PROTEIN-COUPLED RECEPTORS IN ENDOSOMES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-02-03 | — | — | US | claimed |
| EP-2276475-B1 | BIODEGRADABLE NANOSHELLS FOR DELIVERY OF THERAPEUTIC AND/OR IMAGING MOLECULES | NAT UNIV IRELAND GALWAY (IE) | 2021-11-03 | — | — | EP | claimed |
| EP-3741780-B1 | RUBBER COMPOSITION FOR TIRE TREAD AND TIRE MANUFACTURED BY USING SAME | HANKOOK TIRE & TECH CO LTD (KR) | 2021-05-12 | — | — | EP | claimed |
| US-20200369085-A1 | RUBBER COMPOSITION FOR TIRE TREAD AND TIRE MANUFACTURED BY USING SAME | HANKOOK TIRE & TECHNOLOGY CO., LTD. (KR) | 2020-11-26 | — | — | US | claimed |
| US-6828025-B2 | Using controlled/living polymerization to ensure preparation of an amphiphilic copolymer in suspension polymerization conditions; polymerization carried out by atom transfer radical polymerization | MCMASTER UNIVERSITY (CA) | 2004-12-07 | — | — | US | claimed |
| US-20040203149-A1 | Composite materials comprising supported porous gels | MERCK MILLIPORE LTD. (IE) | 2004-10-14 | — | — | US | claimed |
| US-20040032038-A1 | Microencapsulation of polar liquids in copolymer shells | MCMASTER UNIVERSITY (CA) | 2004-02-19 | — | — | US | claimed |
| US-6673886-B2 | FOR INTRAOCULAR LENSES | BAUSCH & LOMB INCORPORATED | 2004-01-06 | — | — | US | claimed |
| US-20030181613-A1 | Amphiphilic diblock, triblock and star-block copolymers and their pharmaceutical compositions | ENDO GLOBAL VENTURES (BM) | 2003-09-25 | — | — | US | claimed |
| US-6511769-B1 | Lithium salt, solvent, and thermosetting resin comprising a polyoxyethylene glycol acrylate | SAMSUNG SDI CO., LTD (KR) | 2003-01-28 | — | — | US | claimed |
| US-6451895-B1 | One step process for making breathable, clay filled polymer compositions having controlled stability in contact with aqueous fluids | KIMBERLY-CLARK WORLDWIDE, INC. | 2002-09-17 | — | — | US | claimed |
| US-6407160-B2 | POLYMER PARTICLE COMPRISING A WAX PHASE OF GIVEN MELTING POINT AND A POLYMER PHASE OF A COPOLYMER OF A MONOMER THAT WOULD FORM A WATER SOLUBLE HOMOPOLYMER AND ONE THAT WOULD FORM A WATER INSOLUBLE HOMOPOLYMER; FORMS STABLE DISPERSIONS | EASTMAN KODAK COMPANY | 2002-06-18 | — | — | US | claimed |
| US-6075118-A | A MELT BLEND COMPRISING A POLY(VINYL ALCOHOL) AND A POLYLACTIDE, WHEREIN THE POLYLACTIDE IS GRAFTED WITH A POLAR MONOMER, OLIGOMER OR POLYMER OR MIXTURE ONTO ITS BACKBONE | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2000-06-13 | — | — | US | claimed |
| US-4548844-A | IMPARTS LUBRICANT AND MOISTURE TRANSMISSION PROPERTIES | Podell, Howard I. (US) | 1985-10-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220031849-A1 | NANOPARTICLE ENCAPSULATION TO TARGET G PROTEIN-COUPLED RECEPTORS IN ENDOSOMES | GPR88, GPR65, ARRB1 | TSHR 1125/4885MAPK1 2007/4885MEN1 3215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.