SCHEMBL8977381

SCHEMBL8977381

CCCCCc1ccc2cc(-c3cnc(CCCCCC(C)F)nc3)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.39
RAB9A P51151 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPC1 O15118 1/20 0.38
STAT3 P40763 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
BDKRB2 P30411 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8977321 0.87 SRC (0.38) KDM4EALDH1A1HPGDL3MBTL1RARB
SCHEMBL8977266 0.85 RARB (0.48) MAPTRAB9ASMN1; SMN2KDM4EMEN1
SCHEMBL7559220 0.84 CNR2 (0.33)
SCHEMBL7559408 0.84 GRIN2D (0.32) SPHK1
SCHEMBL7556697 0.78 FTO (0.34)
SCHEMBL8600962 0.77 SPHK1 (0.32) SPHK1
SCHEMBL7559183 0.77 SRC (0.41) MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL6294017 0.77 PTGS2 (0.50) MAPTKDM4EMEN1ALDH1A1KMT2A
SCHEMBL9584500 0.76 CYP2D6 (0.44) MAPTRAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL8977263 0.76 TLR8 (0.42) MAPTRAB9ASMN1; SMN2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708165-A1 Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-24 EP disclosed