Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 8/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CHRND | Q07001 | 1/20 | 0.32 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051305 | 0.74 | CHRNB2 (0.32) | CHRNB2CHRNA3CHRNA7NPC1HTT | |
| SCHEMBL8977319 | 0.72 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL8514392 | 0.66 | CHRNB2 (0.43) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL2408324 | 0.66 | CHRNB2 (0.43) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL9050188 | 0.65 | CHRNB2 (0.46) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL9047337 | 0.65 | CHRNB2 (0.46) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL25326601 | 0.62 | CHRNB2 (0.44) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL30530026 | 0.62 | CHRNB2 (0.45) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL16166328 | 0.61 | CHRNB2 (0.45) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL12190731 | 0.61 | CHRNB2 (0.53) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545741-A | Process for the preparation of epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1996-08-13 | — | — | US | disclosed |