Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977389 | 0.72 | CHRNB2 (0.35) | — | |
| SCHEMBL9049929 | 0.70 | MAPT (0.38) | SMN1; SMN2MAPT | |
| SCHEMBL8977326 | 0.70 | MAPT (0.38) | SMN1; SMN2MAPT | |
| SCHEMBL9050784 | 0.63 | KDM1A (0.38) | SMN1; SMN2MAPT | |
| SCHEMBL8977393 | 0.63 | KDM1A (0.38) | SMN1; SMN2MAPT | |
| SCHEMBL9051305 | 0.62 | CHRNB2 (0.32) | — | |
| SCHEMBL29364733 | 0.59 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPT | |
| SCHEMBL30530026 | 0.59 | CHRNB2 (0.45) | — | |
| SCHEMBL21384638 | 0.59 | ALDH1A1 (0.39) | SMN1; SMN2MAPT | |
| SCHEMBL8514392 | 0.58 | CHRNB2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545741-A | Process for the preparation of epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1996-08-13 | — | — | US | disclosed |