Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrophenolate SCHEMBL15923356 | 0.83 | NPC1 (0.60) | L3MBTL1THRATHRBKMT2ARECQL | |
| SCHEMBL16861184 | 0.83 | GPR35 (0.51) | L3MBTL1KMT2AGPR35RECQLNPC1 | |
| SCHEMBL17817616 | 0.82 | ESR1 (0.47) | ESR1L3MBTL1THRATHRBKMT2A | |
| SCHEMBL10387780 | 0.82 | ESR1 (0.50) | ESR1L3MBTL1THRATHRBKMT2A | |
| Nitrophenolate SCHEMBL7601509 | 0.81 | ESR1 (0.49) | ESR1L3MBTL1THRATHRBKMT2A | |
| SCHEMBL8977411 | 0.81 | MAPT (0.47) | L3MBTL1THRATHRBKMT2APLA2G4B | |
| SCHEMBL27544915 | 0.81 | NR5A1 (0.53) | KMT2AMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL17817064 | 0.80 | L3MBTL1 (0.43) | ESR1L3MBTL1THRATHRBKMT2A | |
| SCHEMBL8581954 | 0.79 | NPC1 (0.72) | L3MBTL1THRATHRBKMT2ARECQL | |
| SCHEMBL18012379 | 0.79 | NPC1 (0.72) | L3MBTL1THRATHRBKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147864-A | Bronchodilator agent, antianaphylactic agent, antishock agent, cardiotonic agent and anticarcinogenic agent | AMERICAN CYANAMID COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-4983592-A | Bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0374513-A2 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |