Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977527 | 0.83 | MMP2 (0.45) | MMP2MMP3TDP1POLBAPEX1 | |
| SCHEMBL8631711 | 0.79 | POLB (0.47) | TDP1POLBAPEX1HTTCHRM3 | |
| SCHEMBL8977523 | 0.79 | STAT3 (0.42) | STAT3MMP2MMP3LTB4R2TSHR | |
| SCHEMBL3317465 | 0.78 | TSHR (0.43) | TDP1POLBAPEX1HTTKMT2A | |
| SCHEMBL29316150 | 0.74 | POLB (0.58) | MMP2MMP3TDP1POLBAPEX1 | |
| SCHEMBL14275377 | 0.74 | POLB (0.61) | MMP2MMP3TDP1POLBAPEX1 | |
| SCHEMBL2468868 | 0.73 | HTT (0.64) | MMP2MMP3TDP1POLBAPEX1 | |
| SCHEMBL29321879 | 0.73 | TSHR (0.50) | MMP2MMP3TDP1POLBAPEX1 | |
| SCHEMBL953146 | 0.73 | HTT (0.64) | MMP2MMP3TDP1POLBAPEX1 | |
| SCHEMBL1484039 | 0.72 | POLB (0.48) | TDP1POLBAPEX1HTTCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463931-B1 | Amorphous copolymers, translucent to visible light, for applications in non linear optics | THOMSON CSF (FR) | 1996-04-24 | — | — | EP | disclosed |
| EP-0463931-A1 | Amorphous copolymers, translucent to visible light, for applications in non linear optics | THOMSON-CSF (FR) | 1992-01-02 | — | — | EP | disclosed |