Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484039 | 0.83 | POLB (0.48) | TSHRPOLBAPEX1HTTTDP1 | |
| O-Xylene SCHEMBL23120128 | 0.78 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL8977546 | 0.78 | STAT3 (0.43) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL8365990 | 0.78 | TDP1 (0.52) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL24522767 | 0.76 | ALDH1A1 (0.41) | LMNAALDH1A1TP53CA1 | |
| SCHEMBL10992757 | 0.76 | RAD52 (0.49) | TSHRHTTTDP1LMNAALDH1A1 | |
| SCHEMBL15910550 | 0.75 | TDP1 (0.54) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL13328823 | 0.75 | TDP1 (0.54) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9472553 | 0.75 | POLB (0.37) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15910936 | 0.74 | TDP1 (0.55) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737237-B2 | Controlled structure copolymer comprising an amphoteric or zwitterionic part | PHODIA CHIMIE (FR) | 2010-06-15 | — | — | US | claimed |