SCHEMBL1484039

SCHEMBL1484039

C=C(C)C(=O)OCCCN(C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.48
APEX1 P27695 1/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
TSHR P16473 2/20 0.45
MTNR1A P48039 9/20 0.41
MTNR1B P49286 9/20 0.41
PPARG P37231 1/20 0.40
THRB P10828 1/20 0.39
BCHE P06276 1/20 0.39
RAD52 P43351 1/20 0.39
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8365990 0.94 TDP1 (0.52) POLBAPEX1HTTTDP1TSHR
SCHEMBL1011170 0.91 POLB (0.43) POLBAPEX1HTTTDP1TSHR
SCHEMBL8857304 0.85 TDP1 (0.48) POLBAPEX1HTTTDP1TSHR
SCHEMBL20746157 0.84 RAD52 (0.52) TDP1MTNR1AMTNR1BPPARGBCHE
SCHEMBL3317465 0.83 TSHR (0.43) POLBAPEX1HTTTDP1TSHR
SCHEMBL8873860 0.81 TDP1 (0.53) POLBAPEX1HTTTDP1TSHR
SCHEMBL31582668 0.80 POLB (0.44) POLBAPEX1HTTTDP1TSHR
SCHEMBL9804650 0.80 RAD52 (0.51) TDP1MTNR1AMTNR1BPPARGBCHE
SCHEMBL1256483 0.80 MTNR1A (0.49) POLBAPEX1HTTTDP1TSHR
SCHEMBL9317009 0.80 MMP14 (0.41) POLBAPEX1HTTTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150094448-A1 SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES MEDIPACS, INC. 2015-04-02 US disclosed
EP-2164880-B1 EMULSION POLYMER COMPRISING ACTIVATORS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF IN TWO-COMPONENT OR MULTICOMPONENT SYSTEMS EVONIK ROEHM GMBH (DE) 2012-06-06 EP disclosed
US-8168736-B2 Emulsion polymer comprising activators, process for preparation thereof and use thereof in two-component or multicomponent systems EVONIK RÖHM GMBH (DE) 2012-05-01 US disclosed
EP-2314556-A2 Two component mortar composition and its use HILTI Aktiengesellschaft (LI) 2011-04-27 EP disclosed
US-20110073327-A1 Two-component mortar composition and method of using same HILTI AKTIENGESELLSCHAFT 2011-03-31 US disclosed
US-20100286331-A1 TWO OR MORE-COMPONENT SYSTEM CURED BY A REDOX INITIATOR SYSTEM WITH CONTROLLABLE WORKING LIFE, AND THE USE THEREOF EVONIK ROEHM GMBH (DE) 2010-11-11 US disclosed
US-20100210784-A1 EMULSION POLYMER COMPRISING ACTIVATORS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF IN TWO-COMPONENT OR MULTICOMPONENT SYSTEMS EVONIK RÖHM GMBH (DE) 2010-08-19 US disclosed
US-20100174028-A1 EMULSION POLYMER COMPRISING ACTIVATORS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF IN TWO-COMPONENT OR MULTICOMPONENT SYSTEMS EVONIK ROEHM GMBH (DE) 2010-07-08 US disclosed
EP-2167559-A1 TWO OR MORE-COMPONENT SYSTEM CURED BY A REDOX INITIATOR SYSTEM WITH CONTROLLABLE WORKING LIFE, AND THE USE THEREOF Evonik Röhm GmbH (DE) 2010-03-31 EP disclosed
EP-2164884-A1 EMULSION POLYMER COMPRISING ACTIVATORS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF IN TWO-COMPONENT OR MULTICOMPONENT SYSTEMS Evonik Röhm GmbH (DE) 2010-03-24 EP disclosed
EP-2164880-A1 EMULSION POLYMER COMPRISING ACTIVATORS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF IN TWO-COMPONENT OR MULTICOMPONENT SYSTEMS Evonik Röhm GmbH (DE) 2010-03-24 EP disclosed
WO-2009007255-A1 EMULSION POLYMER COMPRISING ACTIVATORS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF IN TWO-COMPONENT OR MULTICOMPONENT SYSTEMS EVONIK RÖHM GMBH (DE) 2009-01-15 WO disclosed
WO-2009007254-A1 EMULSION POLYMER COMPRISING ACTIVATORS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF IN TWO-COMPONENT OR MULTICOMPONENT SYSTEMS EVONIK RÖHM GMBH (DE) 2009-01-15 WO disclosed
WO-2009007253-A1 TWO OR MORE-COMPONENT SYSTEM CURED BY A REDOX INITIATOR SYSTEM WITH CONTROLLABLE WORKING LIFE, AND THE USE THEREOF EVONIK RÖHM GMBH (DE) 2009-01-15 WO disclosed