Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.61 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GOT1 | P17174 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24786819 | 0.95 | P2RX7 (0.57) | P2RX7AHRCES1KMT2AFAAH | |
| SCHEMBL3992842 | 0.85 | KMT2A (0.60) | P2RX7AHRCES1KMT2AMEN1 | |
| SCHEMBL2538334 | 0.83 | — | — | |
| SCHEMBL28293 | 0.83 | — | — | |
| SCHEMBL31605465 | 0.83 | — | — | |
| SCHEMBL667511 | 0.81 | — | — | |
| SCHEMBL3721094 | 0.81 | — | — | |
| SCHEMBL19265704 | 0.81 | — | — | |
| SCHEMBL22288333 | 0.81 | P2RX7 (0.57) | P2RX7AHRCES1KMT2AFAAH | |
| SCHEMBL971441 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220399166-A1 | DIELECTRIC COMPOSITION, DIELECTRIC FILM, AND CAPACITOR | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2022-12-15 | — | — | US | disclosed |
| CN-108558834-B | Pyridazinyl three-color fluorescence emission organic luminescent material and application thereof | 广东省测试分析研究所（中国广州分析测试中心） | 2020-01-21 | — | — | CN | disclosed |
| CN-108558834-B | Pyridazinyl three-color fluorescence emission organic luminescent material and application thereof | 广东省测试分析研究所（中国广州分析测试中心） | 2020-01-21 | — | — | CN | disclosed |
| CN-1771050-A | macrocyclic inhibitors of hepatitis c serine protease | ENANTA PHARM INC (US) | 2006-05-10 | — | — | CN | disclosed |
| CN-1216871-C | Pyridazinyl ketone derivative having insect growth regulation activity and its preparation method | UNIV CHINA AGRICULTURAL (CN) | 2005-08-31 | — | — | CN | disclosed |
| CN-1571787-A | Quinuclidine derivatives processes for preparing them and their uses as M2 and/or M3 muscarinic receptor inhibitors | UCB SA (BE) | 2005-01-26 | — | — | CN | disclosed |
| CN-1493564-A | Pyridazinyl ketone derivative having insect growth regulation activity and its preparation method | 中国农业大学 | 2004-05-05 | — | — | CN | disclosed |
| US-5569763-A | USEFUL AS ORGANIC NONLINEAR OPTICAL MATERIAL AND A HIGHLY SENSITIVE COLORING CHELATION AGENT | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-10-29 | — | — | US | disclosed |
| CN-85106742-A | The preparation method of pyridazinylimidazolicompounds compounds | — | 1986-12-31 | — | — | CN | disclosed |