⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977638 | 0.81 | P2RX7 (0.61) | — | |
| SCHEMBL28293 | 0.79 | — | — | |
| SCHEMBL2538334 | 0.79 | — | — | |
| SCHEMBL31605465 | 0.79 | — | — | |
| SCHEMBL24786819 | 0.77 | P2RX7 (0.57) | — | |
| SCHEMBL149156 | 0.77 | — | — | |
| SCHEMBL667511 | 0.77 | — | — | |
| SCHEMBL22288333 | 0.77 | P2RX7 (0.57) | — | |
| Hydrochloric Acid SCHEMBL11797023 | 0.77 | P2RX7 (0.57) | — | |
| SCHEMBL19265704 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902419-B | Novel nucleosides or nucleotide derivatives and use thereof | ST制药株式会社 | 2023-11-24 | — | — | CN | claimed |
| US-11655268-B2 | Nucleoside or nucleotide derivatives, and uses thereof | ST PHARM CO., LTD. (KR) | 2023-05-23 | — | — | US | claimed |
| US-20210040135-A1 | NOVEL NUCLEOSIDE OR NUCLEOTIDE DERIVATIVES, AND USES THEREOF | ST PHARM CO., LTD. (KR) | 2021-02-11 | — | — | US | claimed |
| EP-3744726-A1 | NOVEL NUCLEOSIDE OR NUCLEOTIDE DERIVATIVES, AND USES THEREOF | ST Pharm Co., Ltd. (KR) | 2020-12-02 | — | — | EP | claimed |
| CN-111902419-A | Novel nucleoside or nucleotide derivatives and use thereof | ST制药株式会社 | 2020-11-06 | — | — | CN | claimed |
| EP-1730152-B1 | TETRAHYDROQUINOLINE DERIVATIVES AND A PROCESS FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-05-02 | — | — | EP | claimed |
| US-20110039828-A1 | TETRAHYDROQUINOLINE DERIVATIVES AND A PROCESS FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-02-17 | — | — | US | claimed |
| US-20070082896-A1 | Tetrahydroquinoline derivatives and a process for preparing the same | TANABE SEIYAKU CO., LTD. | 2007-04-12 | — | — | US | claimed |
| US-20070032485-A1 | Tetrahydronaphthyridine derivatives and a process for preparing the same | TANABE SEIYAKU CO., LTD. | 2007-02-08 | — | — | US | claimed |
| EP-1732924-A2 | TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 2006-12-20 | — | — | EP | claimed |
| EP-1730152-A2 | TETRAHYDROQUINOLINE DERIVATIVES AND A PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2006-12-13 | — | — | EP | claimed |
| WO-2005095395-A2 | TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-13 | — | — | WO | claimed |
| WO-2005095409-A2 | TETRAHYDROQUINOLINE DERIVATIVES AND A PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-13 | — | — | WO | claimed |
| CN-117693500-A | Carboxamide derivative and agricultural/horticultural plant disease control agent | 组合化学工业株式会社 | 2024-03-12 | — | — | CN | disclosed |
| CN-111902419-B | Novel nucleosides or nucleotide derivatives and use thereof | ST制药株式会社 | 2023-11-24 | — | — | CN | disclosed |
| US-20230331724-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-10-19 | — | — | US | disclosed |
| EP-0811378-A1 | PREVENTIVE/REMEDY FOR INTERSTITIAL PNEUMONIA, INFLAMMATORY INTESTINAL DISEASES OR VASCULAR THICKENING CONTAINING QUINOLIZINONE COMPOUNDS, SALT THEREOF OR HYDRATES THEREFOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| US-4698349-A | Quinolizinone compounds, and pharmaceutical composition comprising the same, useful as anti-ulcerative and anti-allergic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| US-4650804-A | TETRAZOLYLCARBAMOYL DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-17 | — | — | US | disclosed |
| EP-0157346-A2 | Quinolizinone compound, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-09 | — | — | EP | disclosed |