Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423969 | 0.82 | TUBB4A (0.46) | ALDH1A1KDM4EMAPTHPGDTUBB4A | |
| SCHEMBL24074529 | 0.82 | KDM4E (0.48) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL7566334 | 0.82 | MAPT (0.53) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL2880010 | 0.78 | KDM4E (0.66) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL28987827 | 0.77 | HTR6 (0.46) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL6009595 | 0.77 | TSHR (0.61) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL27324660 | 0.76 | KDM4E (0.43) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL24073034 | 0.76 | NPC1 (0.48) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL27408415 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTRAB9AHPGD | |
| SCHEMBL27663999 | 0.74 | TSHR (0.66) | ALDH1A1MAPTRAB9AHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708091-A2 | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |