Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977688 | 1.00 | ALDH1A1 (0.35) | ALDH1A1MAPTCRHBPCRHR2NOS3 | |
| SCHEMBL8977684 | 1.00 | ALDH1A1 (0.35) | ALDH1A1MAPTCRHBPCRHR2NOS3 | |
| SCHEMBL9333332 | 0.93 | IDO1 (0.32) | ALDH1A1NOS3NOS1NOS2HPGD | |
| SCHEMBL9333339 | 0.93 | IDO1 (0.32) | ALDH1A1NOS3NOS1NOS2HPGD | |
| SCHEMBL9333334 | 0.93 | IDO1 (0.32) | ALDH1A1NOS3NOS1NOS2HPGD | |
| SCHEMBL8814742 | 0.84 | IDO1 (0.33) | ALDH1A1 | |
| SCHEMBL8814746 | 0.84 | IDO1 (0.33) | ALDH1A1 | |
| SCHEMBL8977709 | 0.83 | NOS3 (0.36) | ALDH1A1NOS3NOS1NOS2GAA | |
| SCHEMBL8977711 | 0.83 | NOS3 (0.36) | ALDH1A1NOS3NOS1NOS2GAA | |
| SCHEMBL8977706 | 0.83 | NOS3 (0.36) | ALDH1A1NOS3NOS1NOS2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378308-B1 | Acrylate fungicides | AGREVO UK LTD (GB) | 1996-04-10 | — | — | EP | disclosed |
| US-5332752-A | Acrylate fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |
| EP-0378308-A1 | Acrylate fungicides | AgrEvo UK Limited (GB) | 1990-07-18 | — | — | EP | disclosed |