Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333339 | 1.00 | IDO1 (0.32) | IDO1OPRM1OPRD1PAX8KDM4E | |
| SCHEMBL9333332 | 1.00 | IDO1 (0.32) | IDO1OPRM1OPRD1PAX8KDM4E | |
| SCHEMBL8977680 | 0.93 | ALDH1A1 (0.35) | NOS3NOS1NOS2ALDH1A1HPGD | |
| SCHEMBL8977684 | 0.93 | ALDH1A1 (0.35) | NOS3NOS1NOS2ALDH1A1HPGD | |
| SCHEMBL8977688 | 0.93 | ALDH1A1 (0.35) | NOS3NOS1NOS2ALDH1A1HPGD | |
| SCHEMBL8977709 | 0.90 | NOS3 (0.36) | NOS3NOS1NOS2ALDH1A1HPGD | |
| SCHEMBL8977711 | 0.90 | NOS3 (0.36) | NOS3NOS1NOS2ALDH1A1HPGD | |
| SCHEMBL8977706 | 0.90 | NOS3 (0.36) | NOS3NOS1NOS2ALDH1A1HPGD | |
| SCHEMBL8814746 | 0.88 | IDO1 (0.33) | IDO1PTGDR2ALDH1A1 | |
| SCHEMBL8814742 | 0.88 | IDO1 (0.33) | IDO1PTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594573-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | AgrEvo UK Limited (GB) | 1994-05-04 | — | — | EP | disclosed |
| US-5264609-A | Etherification and hydrolysis | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-11-23 | — | — | US | disclosed |
| EP-0527182-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | AgrEvo UK Limited (GB) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991017152-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |
| WO-1991007385-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |