Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.69 |
| ▸ | STAT1 | P42224 | 1/20 | 0.69 |
| ▸ | TOP1 | P11387 | 4/20 | 0.52 |
| ▸ | CYCS | P99999 | 4/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455573 | 0.96 | STAT3 (0.67) | STAT3STAT1TOP1CYCSABCG2 | |
| SCHEMBL31550992 | 0.89 | STAT3 (0.86) | STAT3STAT1TOP1CYCSABCG2 | |
| SCHEMBL1224432 | 0.89 | STAT3 (0.86) | STAT3STAT1TOP1CYCSABCG2 | |
| SCHEMBL30293296 | 0.89 | STAT3 (0.86) | STAT3STAT1TOP1CYCSABCG2 | |
| SCHEMBL17841775 | 0.88 | STAT3 (0.84) | STAT3STAT1TOP1CYCSABCG2 | |
| SCHEMBL31324940 | 0.88 | STAT3 (0.84) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL31324939 | 0.88 | STAT3 (0.84) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL24270402 | 0.86 | STAT3 (0.82) | STAT3STAT1TOP1CYCSABCG2 | |
| SCHEMBL6291665 | 0.86 | STAT3 (0.62) | STAT3STAT1TOP1CYCSABCG2 | |
| SCHEMBL2563180 | 0.86 | STAT3 (0.91) | STAT3STAT1TOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5493017-A | Ring-metalated porphyrins | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-02-20 | — | — | US | disclosed |