Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.39 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.32 |
| ▸ | SELE | P16581 | 2/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412359 | 0.77 | MAPT (0.32) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL24982919 | 0.77 | TSHR (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL22906079 | 0.76 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL22897394 | 0.76 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL10495757 | 0.75 | THRA (0.40) | BPTFSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL22897418 | 0.74 | ALDH1A1 (0.32) | TNFRSF1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL22897456 | 0.74 | ALDH1A1 (0.32) | TNFRSF1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10495694 | 0.74 | THRA (0.39) | BPTFSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL10495702 | 0.72 | BPTF (0.35) | BPTF | |
| SCHEMBL10495773 | 0.72 | ALDH1A1 (0.41) | BPTFALDH1A1SMN1; SMN2L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707572-A1 | IODINATED OLIGOMERIC COMPOUNDS AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME | BRACCO S.p.A. (IT) | 1996-04-24 | — | — | EP | disclosed |