Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22906079 | 0.85 | ALDH1A1 (0.33) | MAPTL3MBTL1LMNAKDM4ERECQL | |
| SCHEMBL22897394 | 0.85 | ALDH1A1 (0.33) | MAPTL3MBTL1LMNAKDM4ERECQL | |
| SCHEMBL24982919 | 0.82 | TSHR (0.31) | ALDH1A1 | |
| SCHEMBL22897418 | 0.80 | ALDH1A1 (0.32) | MAPTL3MBTL1KDM4ERECQLALDH1A1 | |
| SCHEMBL22897456 | 0.80 | ALDH1A1 (0.32) | MAPTL3MBTL1KDM4ERECQLALDH1A1 | |
| SCHEMBL25836509 | 0.80 | APP (0.30) | — | |
| SCHEMBL25836627 | 0.79 | ALDH1A1 (0.33) | MAPTL3MBTL1LMNAKDM4ERECQL | |
| SCHEMBL8978058 | 0.77 | CHEK1 (0.39) | MAPTL3MBTL1LMNAKDM4EALDH1A1 | |
| SCHEMBL22897398 | 0.76 | ALDH1A1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL22897396 | 0.75 | L3MBTL1 (0.37) | MAPTL3MBTL1LMNAKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714879-B1 | Biphenyl iodinated derivatives and their diagnostic use | BRACCO SPA (IT) | 1999-08-04 | — | — | EP | claimed |
| US-5663413-A | X-RAY CONTRAST | DIBRA S.P.A. (IT) | 1997-09-02 | — | — | US | claimed |
| EP-0714879-A1 | Biphenyl iodinated derivatives and their diagnostic use | BRACCO S.p.A. (IT) | 1996-06-05 | — | — | EP | claimed |
| EP-0714879-B1 | Biphenyl iodinated derivatives and their diagnostic use | BRACCO SPA (IT) | 1999-08-04 | — | — | EP | disclosed |
| US-5663413-A | X-RAY CONTRAST | DIBRA S.P.A. (IT) | 1997-09-02 | — | — | US | disclosed |
| EP-0714879-A1 | Biphenyl iodinated derivatives and their diagnostic use | BRACCO S.p.A. (IT) | 1996-06-05 | — | — | EP | disclosed |