SCHEMBL3752207

SCHEMBL3752207

C=CCNn1ccc(=O)[nH]c1=O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.40
DDB1 Q16531 1/20 0.37
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
DUT P33316 5/20 0.35
PKM P14618 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8933242 0.74 CRBN (0.41) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL7965647 0.70 ADRA2B (0.40) CRBNDDB1LMNADUTPKM
SCHEMBL16588800 0.70 MAPK1 (0.40) ALDH1A1LMNA
SCHEMBL9763767 0.70 CRBN (0.42) CRBNDUTPKM
SCHEMBL3541014 0.70 CRBN (0.54) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL2181554 0.70 CRBN (0.54) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL4537742 0.69 DUT (0.49) CRBNALDH1A1LMNADUTPKM
SCHEMBL9707667 0.69
SCHEMBL25430771 0.69 GPR84 (0.44) CRBN
SCHEMBL9277788 0.67 CRBN (0.45) CRBNDDB1ALDH1A1LMNADUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120153078-A RNA molecules encoding RSV-F and vaccines containing the same 辉瑞大药厂 2025-06-13 CN disclosed
US-20250163492-A1 METHOD FOR GENERATING POPULATION OF LABELED NUCLEIC ACID MOLECULES AND KIT FOR THE METHOD BGI SHENZHEN (CN) 2025-05-22 US disclosed
US-20250129407-A1 METHOD FOR GENERATING LABELED NUCLEIC ACID MOLECULAR POPULATION AND KIT THEREOF BGI SHENZHEN (CN) 2025-04-24 US disclosed
CN-119604304-A Recombinant RNA molecules comprising an untranslated region or a segment encoding spike protein from the Severe acute respiratory coronavirus 2 Omikovia strain 葛兰素史克生物有限公司 2025-03-11 CN disclosed
US-20250059530-A1 LABELING AND ANALYSIS METHOD FOR SINGLE-CELL NUCLEIC ACID BGI SHENZHEN (CN) 2025-02-20 US disclosed
CN-119431453-A Phosphorus (V) based reagent, method for the production thereof, and use thereof for producing stereoregular organic phosphorus (V) compounds 百时美施贵宝公司 2025-02-14 CN disclosed
CN-119375375-A Method for detecting nucleotide, cap analogue and nucleic acid in vitro transcription product 楷拓生物科技(苏州)有限公司 2025-01-28 CN disclosed
CN-118955655-A GE protein antigen variant, preparation method and application thereof 北京微星生物科技有限公司 2024-11-15 CN disclosed
EP-4455299-A1 METHOD FOR GENERATING LABELED NUCLEIC ACID MOLECULAR POPULATION AND KIT THEREOF BGI Shenzhen (CN) 2024-10-30 EP disclosed
EP-4455306-A1 LABELING AND ANALYSIS METHOD FOR SINGLE-CELL NUCLEIC ACID BGI Shenzhen (CN) 2024-10-30 EP disclosed
CN-114015755-A Method and kit for labeling nucleic acid molecules 中国科学院北京基因组研究所(国家生物信息中心) 2022-02-08 CN disclosed
CN-108430456-B Cancer vaccine 摩登纳特斯有限公司 2022-01-18 CN disclosed
WO-2021202557-A1 SPHERICAL NUCLEIC ACIDS (SNAS) FOR REGULATION OF FRATAXIN EXICURE OPERATING COMPANY (US) 2021-10-07 WO disclosed
CN-112996854-A High purity PEG lipids and uses thereof 摩登纳特斯有限公司 2021-06-18 CN disclosed
CN-112236438-A Novel phosphorus (V) -based reagents, method for the production thereof, and use thereof for producing sterically defined organic phosphorus (V) compounds 百时美施贵宝公司 2021-01-15 CN disclosed
WO-2018170270-A1 VARICELLA ZOSTER VIRUS (VZV) VACCINE MODERNATX, INC. (US) 2018-09-20 WO disclosed
EP-3204499-A1 ANTI-TNF COMPOUNDS Exicure, Inc. (US) 2017-08-16 EP disclosed
WO-2016057549-A1 ANTI-TNF COMPOUNDS AURASENSE THERAPEUTICS, LLC (US) 2016-04-14 WO disclosed
WO-2014183023-A1 USING PLEXIN-A4 AS A BIOMARKER AND THERAPEUTIC TARGET FOR ALZHEIMER'S DISEASE TRUSTEES OF BOSTON UNIVERSITY (US) 2014-11-13 WO disclosed
US-7838270-B2 Target-dependent transcription using deletion mutants of N4 RNA polymerase THE UNIVERSITY OF CHICAGO (US) 2010-11-23 US disclosed