SCHEMBL8978495

SCHEMBL8978495

c1ccc(COOC2CCOCC2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TSHR P16473 3/20 0.39
IDO1 P14902 1/20 0.36
ALDH1A1 P00352 2/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CTSL P07711 1/20 0.36
CTSB P07858 1/20 0.36
CTSK P43235 1/20 0.36
OPRM1 P35372 2/20 0.36
OPRL1 P41146 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
DPP4 P27487 1/20 0.36
AGXT P21549 1/20 0.35
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8879727 0.87 TSHR (0.46) TSHRIDO1CTSLCTSBCTSK
SCHEMBL27512721 0.83 TSHR (0.43) MEN1KMT2ATSHRIDO1ALDH1A1
SCHEMBL31248144 0.81 OPRM1 (0.51) MEN1KMT2ANPSR1TSHRCTSL
SCHEMBL7461849 0.77 CYP3A4 (0.40) NPSR1TSHRIDO1ALDH1A1CTSL
SCHEMBL28179070 0.76 OPRM1 (0.47) MEN1KMT2ANPSR1ALDH1A1MAPK1
SCHEMBL28072324 0.75 CTSL (0.46) TSHRCTSLCTSBCTSKOPRM1
SCHEMBL11244939 0.75 CTSL (0.46) TSHRCTSLCTSBCTSKOPRM1
SCHEMBL23462124 0.75 TSHR (0.44) MEN1KMT2ANPSR1TSHROPRM1
SCHEMBL22602126 0.74 TSHR (0.38) TSHRIDO1ALDH1A1CTSLCTSB
SCHEMBL31662687 0.73 CTSL (0.42) MEN1KMT2ANPSR1CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524246-B1 RESIST MATERIAL AND PROCESS FOR USE DU PONT (US) 1996-05-08 EP disclosed
US-5219711-A Positive image formation utilizing resist material with carbazole diazonium salt acid generator E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-15 US disclosed
US-5212047-A Resist material and process for use E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-18 US disclosed
US-5206317-A RESIST MATERIAL AND PROCESS FOR USE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-04-27 US disclosed
EP-0524246-A1 RESIST MATERIAL AND PROCESS FOR USE. DU PONT (US) 1993-01-27 EP disclosed
WO-1991015807-A1 RESIST MATERIAL WITH CARBAZOLE DIAZONIUM SALT ACID GENERATOR AND PROCESS FOR USE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-17 WO disclosed
WO-1991015810-A1 RESIST MATERIAL AND PROCESS FOR USE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-17 WO disclosed
US-4985332-A Resist material with carbazole diazonium salt acid generator and process for use E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-15 US disclosed