SCHEMBL8978503

SCHEMBL8978503

CCN(CCNC(C)=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 7/20 0.68
MTNR1B P49286 7/20 0.68
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
GAA P10253 2/20 0.62
MAPT P10636 1/20 0.62
HTT P42858 1/20 0.62
GFER P55789 3/20 0.54
TSHR P16473 1/20 0.53
ALDH1A1 P00352 2/20 0.50
LMNA P02545 2/20 0.49
USP2 O75604 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
NOX1 Q9Y5S8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9180518 0.88 KMT2A (0.72) MTNR1AMTNR1BMEN1KMT2ASMN1; SMN2
SCHEMBL8978487 0.85 MEN1 (0.60) MTNR1AMTNR1BMEN1KMT2ASMN1; SMN2
SCHEMBL554715 0.84 KMT2A (0.56) MTNR1AMTNR1BMEN1KMT2ASMN1; SMN2
SCHEMBL9819666 0.84 KMT2A (0.63) MTNR1AMTNR1BMEN1KMT2ASMN1; SMN2
SCHEMBL2156595 0.84 ALDH1A1 (0.55) MTNR1AMTNR1BMEN1KMT2ASMN1; SMN2
SCHEMBL1432654 0.84 MTNR1A (0.48) MTNR1AMTNR1BMEN1KMT2ASMN1; SMN2
SCHEMBL29387324 0.83 GFER (0.63) MTNR1AMTNR1BMEN1KMT2ASMN1; SMN2
SCHEMBL244238 0.83 GFER (0.63) MTNR1AMTNR1BMEN1KMT2ASMN1; SMN2
SCHEMBL4843540 0.83 ALDH1A1 (0.61) MTNR1AMTNR1BMEN1KMT2ASMN1; SMN2
SCHEMBL12513507 0.83 KMT2A (0.65) MTNR1AMTNR1BMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708757-A1 BENZIMIDAZOLE-DERIVATIZED AZO COMPOUNDS AND POLYMERS DERIVED THEREFROM FOR NONLINEAR OPTICS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-01 EP disclosed
EP-0474431-B1 Amphiphilic compounds for sequential monolayer deposition ICI PLC (GB) 1996-03-06 EP disclosed
WO-1995002581-A1 BENZIMIDAZOLE-DERIVATIZED AZO COMPOUNDS AND POLYMERS DERIVED THEREFROM FOR NONLINEAR OPTICS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-01-26 WO disclosed
US-5321084-A Benzimidazole-derivatized azo compounds and polymers derived therefrom for nonlinear optics MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-14 US disclosed
US-5275924-A Non-centrosymmetric; hydrophobic; chromophores IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-01-04 US disclosed
EP-0474431-A1 Amphiphilic compounds for sequential monolayer deposition IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-03-11 EP disclosed