SCHEMBL244238

SCHEMBL244238

CCN(CCNC(C)=O)c1cccc(C)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.63
MAPT P10636 4/20 0.55
LMNA P02545 2/20 0.55
USP2 O75604 1/20 0.55
MTNR1A P48039 8/20 0.54
MTNR1B P49286 8/20 0.54
ALDH1A1 P00352 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C19 P33261 1/20 0.51
POLB P06746 1/20 0.50
TP53 P04637 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
GAA P10253 1/20 0.48
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387324 1.00 GFER (0.63) GFERMAPTLMNAUSP2MTNR1A
SCHEMBL10620447 0.86 GFER (0.55) GFERMAPTLMNAUSP2ALDH1A1
SCHEMBL4843540 0.86 ALDH1A1 (0.61) GFERMAPTMTNR1AMTNR1BALDH1A1
SCHEMBL11661392 0.84 GFER (0.75) GFERMAPTLMNAUSP2ALDH1A1
SCHEMBL6665261 0.83 MTNR1A (0.52) GFERMAPTMTNR1AMTNR1BMEN1
SCHEMBL11323791 0.83 MTNR1A (0.52) GFERMAPTUSP2MTNR1AMTNR1B
SCHEMBL8978503 0.83 MTNR1A (0.68) GFERMAPTLMNAUSP2MTNR1A
SCHEMBL9060635 0.83 GFER (0.57) GFERMAPTLMNAUSP2ALDH1A1
SCHEMBL27964845 0.82 MTNR1B (0.54) GFERMAPTMTNR1AMTNR1BMEN1
SCHEMBL2725137 0.82 MEN1 (0.68) GFERMAPTLMNAUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021054432-A1 METHOD FOR MEASURING TARGET COMPONENT USING ENZYME, AND MEASUREMENT REAGENT 積水メディカル株式会社 2021-03-25 WO claimed
EP-0411604-B1 Method and kit for determination of components KYOWA MEDEX CO LTD (JP) 1995-02-15 EP claimed
US-5246836-A Colorimetric KYOWA MEDEX CO., LTD. (JP) 1993-09-21 US claimed
EP-0411604-A2 Method and kit for determination of components KYOWA MEDEX CO.LTD. (JP) 1991-02-06 EP claimed
US-4877727-A Substrate for determining leucine aminopeptidase or gamma-glutamyltranspeptase activity KYOWA MEDEX CO., LTD. (JP) 1989-10-31 US claimed
US-4416982-A REACTING WITH PHENOLIC COMPOUND OR ANILINE COMPOUND IN THE PRESENCE OF PEROXIDASE KYOWA HAKKO KOGYO CO., LTD. (JP) 1983-11-22 US claimed
EP-0012446-B1 ACIDIC URICASE, ITS PRODUCTION AND ITS USE FOR THE DETERMINATION OF URIC ACID KYOWA HAKKO KOGYO CO., LTD (JP) 1983-07-13 EP claimed
EP-0010296-B1 TEST COMPOSITION FOR THE DETERMINATION OF TRIGLYCERIDES AND ITS USE KYOWA HAKKO KOGYO CO., LTD (JP) 1982-12-01 EP claimed
US-4317878-A Test composition containing acidic uricase used for quantitative determination of uric acid in sample KYOWA HAKKO KOGYO CO., LTD. (JP) 1982-03-02 US claimed
EP-0012446-A1 Acidic uricase, its production and its use for the determination of uric acid KYOWA HAKKO KOGYO CO., LTD (JP) 1980-06-25 EP claimed
EP-0010296-A1 Test composition for the determination of triglycerides and its use KYOWA HAKKO KOGYO CO., LTD (JP) 1980-04-30 EP claimed
US-12498366-B2 Measurement method for fibroblast growth factor-23 by forming immunocomplexes CANON MEDICAL DIAGNOSTICS CORPORATION (JP) 2025-12-16 US disclosed
US-12168795-B2 Method for measuring cholesterol in low-density lipoprotein, measurement reagent, and measurement kit HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO., LTD. (JP) 2024-12-17 US disclosed
US-20240402163-A1 Method for Measuring Fibroblast Growth Factor-23 and Reagent Therefor HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO., LTD. (JP) 2024-12-05 US disclosed
US-12092637-B2 Method for measuring fibroblast growth factor-23 and reagent therefor HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO., LTD. (JP) 2024-09-17 US disclosed
EP-0054358-A1 Method for decomposing hydrogen peroxide and application to the determination of an analyte KYOWA HAKKO KOGYO CO., LTD. (JP) 1982-06-23 EP disclosed
US-4317878-A Test composition containing acidic uricase used for quantitative determination of uric acid in sample KYOWA HAKKO KOGYO CO., LTD. (JP) 1982-03-02 US disclosed
US-4273874-A CULTURING STREPTOMYCES, USED FOR QUANTITATIVE DETERMINATION OF URIC ACID, OXIDIZED TO ALLANTOIN KYOWA HAKKO KOGYO CO., LTD. (JP) 1981-06-16 US disclosed
EP-0012446-A1 Acidic uricase, its production and its use for the determination of uric acid KYOWA HAKKO KOGYO CO., LTD (JP) 1980-06-25 EP disclosed
EP-0010296-A1 Test composition for the determination of triglycerides and its use KYOWA HAKKO KOGYO CO., LTD (JP) 1980-04-30 EP disclosed